{"id":116787,"date":"2025-09-03T23:01:08","date_gmt":"2025-09-03T23:01:08","guid":{"rendered":"https:\/\/www.newsbeep.com\/au\/116787\/"},"modified":"2025-09-03T23:01:08","modified_gmt":"2025-09-03T23:01:08","slug":"computer-model-makes-nfl-against-the-spread-over-under-money-line-picks-for-each-week-1-game","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/au\/116787\/","title":{"rendered":"Computer model makes NFL against the spread, over\/under, money-line picks for each Week 1 game"},"content":{"rendered":"

The 2025 NFL regular season kicks off on Thursday, with the defending Super Bowl champion Philadelphia Eagles<\/a>\u00a0(-8.5) hosting the Dallas Cowboys<\/a> in the 2025 NFL Kickoff Game. Week 1 spans Thursday through Monday, highlighted by a Friday international matchup in S\u00e3o Paulo between the Kansas City Chiefs (-3) and Los Angeles Chargers<\/a>, and a Sunday Night Football showdown featuring the Baltimore Ravens against the Buffalo Bills (-1.5). The opening weekend also features heavyweight matchups like the Lions (-2.5) vs. Packers and 49ers<\/a>\u00a0(-2.5) vs. Seahawks<\/a>.<\/p>\n

Who should you back in each of the 16 games on the Week 1 NFL schedule, and how should you handle all your NFL money line, NFL over\/under and NFL against the spread spread picks? Before making any Week 1 NFL picks or Week 1 NFL score predictions, you need to see the NFL against the spread, NFL over\/under, and NFL money-line predictions powered by the SportsLine computer simulation model<\/a>.<\/p>\n

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model went 31-15 on top-rated picks in 2024. Anyone following has seen huge returns.<\/p>\n

For Week 1\u00a0NFL betting<\/a>, the model has evaluated the NFL odds<\/a> and provided picks for all 16 games. You can only see the simulation model’s predictions for the Week 1 NFL schedule here<\/a>. Also, can also target the\u00a0DraftKings promo code<\/a>, which offers\u00a0$300 in bonus bets instantly plus over $200 off NFL Sunday Ticket<\/a>:<\/p>\n

Top Week 1 NFL simulation picks<\/p>\n

After analyzing every game in Week 1, the model says the Commanders<\/a> cover comfortably as 6-point home favorites against the Giants<\/a> on Sunday in a game the model projects will go Over the total (45.5) in nearly 70% of simulations. The Commanders are coming off a surprise run to the NFC Championship Game last year, and enter the 2025 season with championship expectations. DraftKings Sportsbook lists Washington with a projected regular season win total of 9.5.<\/p>\n

The Commanders are paced by one of the top young quarterbacks in the NFL in Jayden Daniels<\/a>. The reigning NFL Offensive Rookie of the Year was outstanding in 2025, and Washington gave him another explosive weapon during the offseason in All-Pro wide receiver Deebo Samuel<\/a>. Defensively, the Commanders also boast one of the premier front sevens in the league — a group that was bolstered by the offseason addition of Super Bowl 50 MVP Von Miller<\/a>.\u00a0See its other Week 1 predictions and football picks at SportsLine<\/a>.<\/p>\n

How to make Week 1 NFL computer picks<\/p>\n

In addition, the model has generated three other highly-coveted A-graded picks for Week 1, which includes an underdog winning outright on the moneyline. You can only see the model’s picks and analysis at SportsLine<\/a>.<\/p>\n

Who wins and covers each Week 1 NFL game, and which A-graded picks should you target now? Visit SportsLine now to see the top NFL against the spread, over\/under, and moneyline picks, all from the computer simulation model that is up over $7,000 since its inception<\/a>, and find out.<\/p>\n","protected":false},"excerpt":{"rendered":"The 2025 NFL regular season kicks off on Thursday, with the defending Super Bowl champion Philadelphia Eagles\u00a0(-8.5) hosting…\n","protected":false},"author":2,"featured_media":116788,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[559],"tags":[64,63,1242,593,85,1272],"class_list":["post-116787","post","type-post","status-publish","format-standard","has-post-thumbnail","category-nfl","tag-au","tag-australia","tag-new-york-giants","tag-nfl","tag-sports","tag-washington-commanders"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/116787","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/comments?post=116787"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/116787\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media\/116788"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media?parent=116787"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/categories?post=116787"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/tags?post=116787"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}