{"id":299107,"date":"2025-11-21T11:00:08","date_gmt":"2025-11-21T11:00:08","guid":{"rendered":"https:\/\/www.newsbeep.com\/au\/299107\/"},"modified":"2025-11-21T11:00:08","modified_gmt":"2025-11-21T11:00:08","slug":"nfl-week-12-picks-straight-up-and-against-spread-who-wins-best-games","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/au\/299107\/","title":{"rendered":"NFL Week 12 picks straight up and against spread: Who wins best games?"},"content":{"rendered":"<p><img decoding=\"async\" style=\"position:absolute;top:0;left:0;right:0;bottom:0;width:100%;height:100%;z-index:2\" src=\"https:\/\/www.newsbeep.com\/au\/wp-content\/uploads\/2025\/11\/87355985007-getty-images-2247065480.jpg\"\/><img decoding=\"async\" class=\"vidplayicon\" src=\"https:\/\/www.gannett-cdn.com\/appservices\/universal-web\/universal\/icons\/icon-play-alt-white.svg\" alt=\"play\" style=\"height:40px;margin:auto 18px auto 27px;width:40px\"\/><\/p>\n<p>NFL Week 12 picks: Consider Browns, Vikings and Eagles<\/p>\n<p>Lorenzo Reyes went 2-1 with his picks last week and he&#8217;s ready to carry that energy over to Week 12&#8217;s slate.<\/p>\n<p><a href=\"https:\/\/sportsdata.usatoday.com\/football\/nfl\/schedule?week=12\" rel=\"nofollow noopener\" target=\"_blank\">Week 12<\/a> of the 2025 <a href=\"https:\/\/www.usatoday.com\/sports\/nfl\" rel=\"nofollow noopener\" target=\"_blank\">NFL<\/a> season doesn&#8217;t project as the most appealing on this year&#8217;s schedule, but the biggest returns are often borne of the lowest expectations.<\/p>\n<p>Thursday night&#8217;s game between the <a href=\"https:\/\/www.usatoday.com\/sports\/nfl\/buffalo-bills\" rel=\"nofollow noopener\" target=\"_blank\">Buffalo Bills<\/a> and <a href=\"https:\/\/www.usatoday.com\/sports\/nfl\/houston-texans\" rel=\"nofollow noopener\" target=\"_blank\">Houston Texans<\/a> was viewed as a matchup of perennial division winners when it was set. Now, it&#8217;s a pairing of two teams hoping to secure wild-card berths even as Houston tries to navigate another game without <a href=\"https:\/\/www.usatoday.com\/story\/sports\/nfl\/texans\/2025\/11\/18\/cj-stroud-injury-update-playing-status-bills-texans-quarterback\/87340427007\/\" rel=\"nofollow noopener\" target=\"_blank\">injured QB C.J. Stroud<\/a>.<\/p>\n<p>What seem like Sunday&#8217;s top contests also come with major asterisks. <a href=\"https:\/\/www.usatoday.com\/story\/sports\/nfl\/steelers\/2025\/11\/18\/aaron-rodgers-injury-update-pittsburgh-steelers-quarterback\/87337171007\/\" rel=\"nofollow noopener\" target=\"_blank\">Will QB Aaron Rodgers suit up<\/a> for <a href=\"https:\/\/www.usatoday.com\/sports\/nfl\/pittsburgh-steelers\" rel=\"nofollow noopener\" target=\"_blank\">Steelers<\/a>&#8211;<a href=\"https:\/\/www.usatoday.com\/sports\/nfl\/chicago-bears\" rel=\"nofollow noopener\" target=\"_blank\">Bears<\/a>? Will <a href=\"https:\/\/www.usatoday.com\/story\/sports\/nfl\/packers\/2025\/11\/17\/josh-jacobs-return-injury-update-timeline-packers\/87316377007\/\" rel=\"nofollow noopener\" target=\"_blank\">RB Josh Jacobs be available<\/a> for the <a href=\"https:\/\/www.usatoday.com\/sports\/nfl\/minnesota-vikings\" rel=\"nofollow noopener\" target=\"_blank\">Minnesota Vikings<\/a>&#8216; visit to the <a href=\"https:\/\/www.usatoday.com\/sports\/nfl\/green-bay-packers\" rel=\"nofollow noopener\" target=\"_blank\">Green Bay Packers<\/a>? Might <a href=\"https:\/\/www.usatoday.com\/story\/sports\/nfl\/2025\/11\/19\/joe-burrow-practice-injury-update-status-week-12\/87359188007\/\" rel=\"nofollow noopener\" target=\"_blank\">QB Joe Burrow even make a surprise return<\/a> when the <a href=\"https:\/\/www.usatoday.com\/sports\/nfl\/cincinnati-bengals\" rel=\"nofollow noopener\" target=\"_blank\">Cincinnati Bengals<\/a> host the <a href=\"https:\/\/www.usatoday.com\/sports\/nfl\/new-england-patriots\" rel=\"nofollow noopener\" target=\"_blank\">New England Patriots<\/a>?<\/p>\n<p>What is certain is that rookie <a href=\"https:\/\/www.usatoday.com\/sports\/nfl\/cleveland-browns\" rel=\"nofollow noopener\" target=\"_blank\">Cleveland Browns<\/a> rookie QB Shedeur Sanders will make <a href=\"https:\/\/www.usatoday.com\/story\/sports\/nfl\/browns\/2025\/11\/19\/shedeur-sanders-browns-start-week-12\/87229903007\/\" rel=\"nofollow noopener\" target=\"_blank\">his first regular-season start<\/a> against the <a href=\"https:\/\/www.usatoday.com\/sports\/nfl\/las-vegas-raiders\" rel=\"nofollow noopener\" target=\"_blank\">Raiders<\/a> in Las Vegas. What&#8217;s fairly certain is that the .500 <a href=\"https:\/\/www.usatoday.com\/sports\/nfl\/kansas-city-chiefs\" rel=\"nofollow noopener\" target=\"_blank\">Kansas City Chiefs<\/a> need to beat the first-place <a href=\"https:\/\/www.usatoday.com\/sports\/nfl\/indianapolis-colts\" rel=\"nofollow noopener\" target=\"_blank\">Indianapolis Colt<\/a>s if they&#8217;re going to <a href=\"https:\/\/www.usatoday.com\/story\/sports\/nfl\/2025\/11\/16\/nfl-playoff-picture-week-11-afc-nfc-seeds-eagles-lions-49ers\/87313261007\/\" rel=\"nofollow noopener\" target=\"_blank\">keep their postseason hopes viable<\/a>.<\/p>\n<p>Rounding out the prime-time slate, the <a href=\"https:\/\/www.usatoday.com\/sports\/nfl\/los-angeles-rams\" rel=\"nofollow noopener\" target=\"_blank\">Los Angeles Rams<\/a> \u2212 maybe the league&#8217;s top team \u2212 will welcome the <a href=\"https:\/\/www.usatoday.com\/sports\/nfl\/tampa-bay-buccaneers\" rel=\"nofollow noopener\" target=\"_blank\">Tampa Bay Bucs<\/a>, who are also atop their division, on Sunday night. On Monday, the <a href=\"https:\/\/www.usatoday.com\/sports\/nfl\/carolina-panthers\" rel=\"nofollow noopener\" target=\"_blank\">Carolina Panthers<\/a> and <a href=\"https:\/\/www.usatoday.com\/sports\/nfl\/san-francisco-49ers\" rel=\"nofollow noopener\" target=\"_blank\">San Francisco 49ers<\/a> will meet in Silicon Valley in a game that actually has significant <a href=\"https:\/\/www.usatoday.com\/story\/sports\/nfl\/2025\/11\/16\/nfl-playoff-picture-week-11-afc-nfc-seeds-eagles-lions-49ers\/87313261007\/\" rel=\"nofollow noopener\" target=\"_blank\">playoff implications<\/a> for both squads.<\/p>\n<p>How will the chips fall? Here&#8217;s how USA TODAY Sports&#8217; panel of NFL experts view things:<\/p>\n<p>(<a href=\"https:\/\/www.usatoday.com\/online-betting\/sports\/betmgm\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Odds provided by BetMGM<\/a>)<\/p>\n<p>NFL Week 12 picks, predictions, odds<\/p>\n<p>All NFL news on and off the field.\u00a0<a href=\"https:\/\/profile.usatoday.com\/newsletters\/4th-and-monday\/?ipid=signuptop10\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Sign up<\/a>\u00a0for USA TODAY&#8217;s 4th and Monday newsletter.<\/p>\n","protected":false},"excerpt":{"rendered":"NFL Week 12 picks: Consider Browns, Vikings and Eagles Lorenzo Reyes went 2-1 with his picks last week&hellip;\n","protected":false},"author":2,"featured_media":299108,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[559],"tags":[603,626,256,620,634,617,2872,64,63,9826,5360,615,13246,5349,23166,42498,1261,610,148357,5377,17412,1257,10027,1252,6115,1238,5354,618,6008,596,6007,5145,1255,619,934,1246,98134,609,629,12974,19353,2874,1250,2871,1263,5387,1239,621,637,324,44,593,633,323,335,5357,5345,5378,604,43923,17600,43924,1244,588,17601,85,23371,632,635,11499,155,6019,136500,17599,1247,5359,441,2875,17455,616],"class_list":{"0":"post-299107","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-nfl","8":"tag-aaron","9":"tag-aaron-rodgers","10":"tag-ai","11":"tag-american","12":"tag-american-football","13":"tag-and","14":"tag-angeles","15":"tag-au","16":"tag-australia","17":"tag-bay","18":"tag-bengals","19":"tag-betting","20":"tag-bills","21":"tag-browns","22":"tag-buccaneers","23":"tag-buffalo","24":"tag-buffalo-bills","25":"tag-burrow","26":"tag-c-j","27":"tag-c-j-stroud","28":"tag-carolina","29":"tag-carolina-panthers","30":"tag-cincinnati","31":"tag-cincinnati-bengals","32":"tag-cleveland","33":"tag-cleveland-browns","34":"tag-colts","35":"tag-disclaimer","36":"tag-enabled","37":"tag-football","38":"tag-highlights","39":"tag-houston","40":"tag-houston-texans","41":"tag-hub","42":"tag-indianapolis","43":"tag-indianapolis-colts","44":"tag-jacobs","45":"tag-joe","46":"tag-joe-burrow","47":"tag-josh","48":"tag-josh-jacobs","49":"tag-las","50":"tag-las-vegas-raiders","51":"tag-los","52":"tag-los-angeles-rams","53":"tag-minnesota","54":"tag-minnesota-vikings","55":"tag-national","56":"tag-national-sports","57":"tag-neutral","58":"tag-news","59":"tag-nfl","60":"tag-nfl-hub","61":"tag-overall","62":"tag-overall-neutral","63":"tag-panthers","64":"tag-raiders","65":"tag-rams","66":"tag-rodgers","67":"tag-sanders","68":"tag-scores","69":"tag-shedeur","70":"tag-shedeur-sanders","71":"tag-sport","72":"tag-sport-scores-u0026-statistics","73":"tag-sports","74":"tag-sports-betting","75":"tag-sports-betting-widget-and-disclaimer","76":"tag-sports-news","77":"tag-statistics","78":"tag-story","79":"tag-story-highlights-ai-enabled","80":"tag-stroud","81":"tag-tampa","82":"tag-tampa-bay-buccaneers","83":"tag-texans","84":"tag-u0026","85":"tag-vegas","86":"tag-vikings","87":"tag-widget"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/299107","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/comments?post=299107"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/299107\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media\/299108"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media?parent=299107"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/categories?post=299107"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/tags?post=299107"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}