{"id":321941,"date":"2025-12-02T03:57:09","date_gmt":"2025-12-02T03:57:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/au\/321941\/"},"modified":"2025-12-02T03:57:09","modified_gmt":"2025-12-02T03:57:09","slug":"glp-1-treatment-benefits-vanish-for-most-after-withdrawal-jama-study","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/au\/321941\/","title":{"rendered":"GLP-1 treatment benefits vanish for most after withdrawal: JAMA study"},"content":{"rendered":"<p>More research suggests health impacts may be\u00a0short-lived\u00a0for many patients once they stop taking GLP-1 receptor agonists.<\/p>\n<p>Researchers have tracked 308 patients who underwent nine months of treatment with tirzepatide before stopping, finding that 96% gained weight in the year after withdrawing, including 9% who ended with more weight than they had before treatment.<\/p>\n<p>Patients who regained the most weight also saw the largest rebound in terms of blood pressure and glucose levels.<\/p>\n<p>The findings, published in JAMA Internal Medicine last month, are the first to show a clear association between weight regain and negative cardiometabolic changes following\u00a0tirzepatide\u00a0withdrawal, according to the US researchers.<\/p>\n<p>\t\t\u00d7<\/p>\n<p>\n\t\t\t\tSign in\n\t\t\t<\/p>\n<p class=\"d-none message adg-password-reset\">\n\t\t\t\tIf this is your first visit to the new AusDoc website, reset your password<br \/>\n\t\t\t\t<a class=\"adg-reset_password_link\" href=\"https:\/\/www.ausdoc.com.au\/wp-login.php?action=lostpassword\" target=\"_blank\" rel=\"nofollow noopener\">here.<\/a>\n\t\t\t<\/p>\n","protected":false},"excerpt":{"rendered":"More research suggests health impacts may be\u00a0short-lived\u00a0for many patients once they stop taking GLP-1 receptor agonists. Researchers have&hellip;\n","protected":false},"author":2,"featured_media":321942,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[64,63,91550,137,44],"class_list":["post-321941","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-au","tag-australia","tag-glp-1-ra","tag-health","tag-news"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/321941","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/comments?post=321941"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/321941\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media\/321942"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media?parent=321941"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/categories?post=321941"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/tags?post=321941"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}