{"id":34881,"date":"2025-07-31T12:09:07","date_gmt":"2025-07-31T12:09:07","guid":{"rendered":"https:\/\/www.newsbeep.com\/au\/34881\/"},"modified":"2025-07-31T12:09:07","modified_gmt":"2025-07-31T12:09:07","slug":"why-rare-genetic-diseases-are-not-so-rare-in-india","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/au\/34881\/","title":{"rendered":"Why rare genetic diseases are not so rare in India"},"content":{"rendered":"<p><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/au\/wp-content\/uploads\/2025\/07\/123017651.jpg\" alt=\"\"\/><\/p>\n<p>Thousands of years of endogamy may have shaped genetic disease risk in India. Scientists are now trying to identify those risks in communities<\/p>\n<p>In a crowded lab at the Centre for Cellular and Molecular Biology (CCMB), Kumarasamy Thangaraj points to a machine rotating test tubes that contain tissue from an animal model. The process is one step in a months-long study of a genetic mutation recently discovered in a small South Indian community. The variant, when carried by both parents, can lead to a fatal disease in the child.<br \/>The mutation likely emerged in an ancestor\u2019s genes thousands of years ago, says Thangaraj. And, because they kept marrying within their group, the variant persisted. <\/p>\n","protected":false},"excerpt":{"rendered":"Thousands of years of endogamy may have shaped genetic disease risk in India. Scientists are now trying to&hellip;\n","protected":false},"author":2,"featured_media":34882,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[64,63,21993,31942,31941,10449,336,31940,31939,31938,31937,128],"class_list":["post-34881","post","type-post","status-publish","format-standard","has-post-thumbnail","category-genetics","tag-au","tag-australia","tag-diseases","tag-endogamy-in-india","tag-genetic-mutations","tag-genetic-testing","tag-genetics","tag-kashmirs-gujjars","tag-mutations","tag-rare-genetic-diseases","tag-rise-of-genetic-diseases-in-india","tag-science"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/34881","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/comments?post=34881"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/34881\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media\/34882"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media?parent=34881"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/categories?post=34881"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/tags?post=34881"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}