{"id":37788,"date":"2025-08-01T15:47:11","date_gmt":"2025-08-01T15:47:11","guid":{"rendered":"https:\/\/www.newsbeep.com\/au\/37788\/"},"modified":"2025-08-01T15:47:11","modified_gmt":"2025-08-01T15:47:11","slug":"are-you-really-allergic-to-penicillin-a-pharmacist-explains-why-theres-a-good-chance-youre-not-%e2%88%92-and-how-you-can-find-out-for-sure","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/au\/37788\/","title":{"rendered":"Are you really allergic to penicillin? A pharmacist explains why there\u2019s a good chance you\u2019re not \u2212 and how you can find out for sure"},"content":{"rendered":"<p>Imagine this: You\u2019re at your doctor\u2019s office with a sore throat. The nurse asks, \u201cAny allergies?\u201d And without hesitation you reply, \u201cPenicillin.\u201d It\u2019s something you\u2019ve said for years \u2013 maybe since childhood, maybe because a parent told you so. The nurse nods, makes a note and moves on. <\/p>\n<p>But here\u2019s the kicker: There\u2019s a good chance you\u2019re not actually allergic to penicillin. About 10% to 20% of Americans report that they have a penicillin allergy, yet <a href=\"https:\/\/doi.org\/10.1016\/j.anai.2010.08.002\" rel=\"nofollow noopener\" target=\"_blank\">fewer than 1% actually do<\/a>. <\/p>\n<p>I\u2019m a <a href=\"https:\/\/pharmacy.auburn.edu\/directory\/elizabeth-covington.php\" rel=\"nofollow noopener\" target=\"_blank\">clinical associate professor of pharmacy<\/a> specializing in infectious disease. I study antibiotics and drug allergies, including ways to determine whether people have <a href=\"https:\/\/doi.org\/10.3390\/pharmacy7020069\" rel=\"nofollow noopener\" target=\"_blank\">penicillin allergies<\/a>. <\/p>\n<p>I know <a href=\"https:\/\/scholar.google.com\/citations?user=xC3XXhgAAAAJ&amp;hl=en\" rel=\"nofollow noopener\" target=\"_blank\">from my research<\/a> that incorrectly being labeled as allergic to penicillin can prevent you from getting the most appropriate, safest treatment for an infection. It can also put you at an increased risk of <a href=\"https:\/\/theconversation.com\/antibiotic-resistance-is-at-a-crisis-point-government-support-for-academia-and-big-pharma-to-find-new-drugs-could-help-defeat-superbugs-169443\" rel=\"nofollow noopener\" target=\"_blank\">antimicrobial resistance<\/a>, which is when an antibiotic no longer works against bacteria. <\/p>\n<p>The good news? It\u2019s gotten a lot easier in recent years to pin down the truth of the matter. More and more clinicians now recognize that <a href=\"https:\/\/doi.org\/10.1001\/jamapediatrics.2023.6100\" rel=\"nofollow noopener\" target=\"_blank\">many penicillin allergy labels are incorrect<\/a> \u2013 and there are safe, simple ways to find out your actual allergy status.<\/p>\n<p>A steadfast lifesaver<\/p>\n<p>Penicillin, <a href=\"https:\/\/www.acs.org\/education\/whatischemistry\/landmarks\/flemingpenicillin.html\" rel=\"nofollow noopener\" target=\"_blank\">the first antibiotic drug<\/a>, was <a href=\"https:\/\/wwwnc.cdc.gov\/eid\/article\/23\/5\/16-1556_article\" rel=\"nofollow noopener\" target=\"_blank\">discovered in 1928<\/a> when a physician named Alexander Fleming extracted it from a type of mold called penicillium. It became widely used to treat infections <a href=\"https:\/\/theconversation.com\/guns-not-roses-heres-the-true-story-of-penicillins-first-patient-178463\" rel=\"nofollow noopener\" target=\"_blank\">in the 1940s<\/a>. Penicillin and closely related antibiotics such as <a href=\"https:\/\/medlineplus.gov\/druginfo\/meds\/a685001.html\" rel=\"nofollow noopener\" target=\"_blank\">amoxicillin<\/a> and <a href=\"https:\/\/www.mayoclinic.org\/drugs-supplements\/amoxicillin-and-clavulanate-oral-route\/description\/drg-20072709\" rel=\"nofollow noopener\" target=\"_blank\">amoxicillin\/clavulanate<\/a>, which goes by the brand name Augmentin, are frequently prescribed to treat common infections such as ear infections, strep throat, urinary tract infections, pneumonia and dental infections. <\/p>\n<p>Penicillin antibiotics are a class of narrow-spectrum antibiotics, which means they target specific types of bacteria. People who report having a penicillin allergy are more likely to receive <a href=\"https:\/\/my.clevelandclinic.org\/health\/treatments\/16386-antibiotics\" rel=\"nofollow noopener\" target=\"_blank\">broad-spectrum antibiotics<\/a>. Broad-spectrum antibiotics kill many types of bacteria, <a href=\"https:\/\/theconversation.com\/a-healthy-microbiome-builds-a-strong-immune-system-that-could-help-defeat-covid-19-145668\" rel=\"nofollow noopener\" target=\"_blank\">including helpful ones<\/a>, making it easier for resistant bacteria to survive and spread. This overuse speeds up the development of <a href=\"https:\/\/doi.org\/10.1016\/j.anai.2010.08.002\" rel=\"nofollow noopener\" target=\"_blank\">antibiotic resistance<\/a>. Broad-spectrum antibiotics can also be less effective and are often costlier. <\/p>\n<\/p>\n<p>            Figuring out whether you\u2019re really allergic to penicillin is easier than it used to be.<\/p>\n<p>Why the mismatch?<\/p>\n<p>People often get labeled as <a href=\"https:\/\/doi.org\/10.1542\/peds.2017-2497\" rel=\"nofollow noopener\" target=\"_blank\">allergic to antibiotics as children<\/a> when they have a reaction such as a rash after taking one. But skin rashes frequently occur alongside infections in childhood, with <a href=\"https:\/\/www.chop.edu\/parents-pack\/rash-information\" rel=\"nofollow noopener\" target=\"_blank\">many viruses and infections actually causing rashes<\/a>. If a child is taking an antibiotic at the time, they may be labeled as allergic even though the rash may have been caused by the illness itself. <\/p>\n<p>Some <a href=\"https:\/\/medlineplus.gov\/antibiotics.html\" rel=\"nofollow noopener\" target=\"_blank\">side effects<\/a> such as nausea, diarrhea or headaches can happen with antibiotics, but they don\u2019t always mean you are allergic. These common reactions usually go away on their own or can be managed. A doctor or pharmacist can talk to you about ways to reduce these side effects. <\/p>\n<p>People also often assume penicillin allergies run in families, but having a relative with an allergy doesn\u2019t mean you\u2019re allergic \u2013 <a href=\"https:\/\/doi.org\/10.1001\/jamapediatrics.2023.6100\" rel=\"nofollow noopener\" target=\"_blank\">it\u2019s not hereditary<\/a>. <\/p>\n<p>Finally, about 80% of patients with a true penicillin allergy will <a href=\"https:\/\/doi.org\/10.1016\/j.anai.2010.08.002\" rel=\"nofollow noopener\" target=\"_blank\">lose the allergy<\/a> after about 10 years. That means even if you used to be allergic to this antibiotic, you might not be anymore, depending on the timing of your reaction. <\/p>\n<p>Why does it matter if I have a penicillin allergy?<\/p>\n<p>Believing you\u2019re allergic to penicillin when you\u2019re not can negatively affect your health. For one thing, you are more likely to receive stronger, <a href=\"https:\/\/doi.org\/10.1016\/j.anai.2010.08.002\" rel=\"nofollow noopener\" target=\"_blank\">broad-spectrum antibiotics<\/a> that aren\u2019t always the best fit and can have more side effects. You may also be more likely to get an <a href=\"https:\/\/doi.org\/10.1093\/cid\/cix794\" rel=\"nofollow noopener\" target=\"_blank\">infection after surgery<\/a> and to <a href=\"https:\/\/doi.org\/10.4103\/ijam.ijam_48_22\" rel=\"nofollow noopener\" target=\"_blank\">spend longer in the hospital<\/a> when hospitalized for an infection. What\u2019s more, your <a href=\"https:\/\/doi.org\/10.1016\/j.jaip.2017.12.033\" rel=\"nofollow noopener\" target=\"_blank\">medical bills could end up higher<\/a> due to using more expensive drugs.<\/p>\n<p>Penicillin and its close cousins are often the best tools doctors have to treat many infections. If you\u2019re not truly allergic, figuring that out can open the door to safer, more effective and more affordable treatment options. <\/p>\n<p>            <a href=\"https:\/\/images.theconversation.com\/files\/682164\/original\/file-20250725-56-pd7jrb.jpg?ixlib=rb-4.1.0&amp;q=45&amp;auto=format&amp;w=1000&amp;fit=clip\" rel=\"nofollow noopener\" target=\"_blank\"><img decoding=\"async\" alt=\"An arm stretched out on an examining table gets pricked with a white needle by the hands of a clinician administering an allergy test.\" class=\"lazyload\" src=\"https:\/\/www.newsbeep.com\/au\/wp-content\/uploads\/2025\/08\/file-20250725-56-pd7jrb.jpg\"  \/><\/a><\/p>\n<p>              A penicillin skin test can safely determine whether you have a penicillin allergy, but a health care professional may also be able to tell by asking you some specific questions.<br \/>\n              <a class=\"source\" href=\"https:\/\/www.gettyimages.com\/detail\/photo\/allergy-tests-royalty-free-image\/1646304278\" rel=\"nofollow noopener\" target=\"_blank\">BSIP\/Collection Mix: Subjects via Getty Images<\/a><\/p>\n<p>How can I tell if I am really allergic to penicillin?<\/p>\n<p>Start by talking to a health care professional such as a doctor or pharmacist. Allergy symptoms can range from a mild, self-limiting rash to severe facial swelling and trouble breathing. A health care professional <a href=\"https:\/\/doi.org\/10.3390\/pharmacy7020069\" rel=\"nofollow noopener\" target=\"_blank\">may ask you several questions<\/a> about your allergies, such as what happened, how soon after starting the antibiotic did the reaction occur, whether treatment was needed, and whether you\u2019ve taken similar medications since then. <\/p>\n<p>These questions can help distinguish between a true allergy and a nonallergic reaction. In many cases, this interview is enough to determine you aren\u2019t allergic. But sometimes, further testing may be recommended. <\/p>\n<p>One way to find out whether you\u2019re really allergic to penicillin is through <a href=\"https:\/\/doi.org\/10.1016\/j.anai.2018.07.041\" rel=\"nofollow noopener\" target=\"_blank\">penicillin skin testing<\/a>, which includes tiny skin pricks and small injections under the skin. These tests use components related to penicillin to <a href=\"https:\/\/www.aaaai.org\/tools-for-the-public\/conditions-library\/allergies\/allergy-testing\" rel=\"nofollow noopener\" target=\"_blank\">safely check for a true allergy<\/a>. If skin testing doesn\u2019t cause a reaction, the next step is usually to take a small dose of amoxicillin while being monitored at your doctor\u2019s office, just to be sure it\u2019s safe.<\/p>\n<p>A study published in 2023 showed that in many cases, skipping the skin test and going <a href=\"https:\/\/doi.org\/10.1001\/jamainternmed.2023.2986\" rel=\"nofollow noopener\" target=\"_blank\">straight to the small test dose<\/a> can also be a safe way to check for a true allergy. In this method, patients take a low dose of amoxicillin and are observed for about 30 minutes to see whether any reaction occurs.<\/p>\n<p>With the right questions, testing and expertise, many people can safely reclaim penicillin as an option for treating common infections.<\/p>\n","protected":false},"excerpt":{"rendered":"Imagine this: You\u2019re at your doctor\u2019s office with a sore throat. The nurse asks, \u201cAny allergies?\u201d And without&hellip;\n","protected":false},"author":2,"featured_media":37789,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[33],"tags":[64,63,137,490],"class_list":{"0":"post-37788","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-medication","8":"tag-au","9":"tag-australia","10":"tag-health","11":"tag-medication"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/37788","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/comments?post=37788"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/37788\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media\/37789"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media?parent=37788"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/categories?post=37788"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/tags?post=37788"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}