{"id":382991,"date":"2025-12-31T17:12:06","date_gmt":"2025-12-31T17:12:06","guid":{"rendered":"https:\/\/www.newsbeep.com\/au\/382991\/"},"modified":"2025-12-31T17:12:06","modified_gmt":"2025-12-31T17:12:06","slug":"us-fda-approves-vanda-pharmaceuticals-motion-sickness-drug","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/au\/382991\/","title":{"rendered":"US FDA approves Vanda Pharmaceuticals’ motion sickness drug"},"content":{"rendered":"

Dec 30 (Reuters) – Vanda Pharmaceuticals (VNDA.O), opens new tab<\/a> said on Tuesday its drug for the prevention of motion-induced vomiting was approved by the U.S. health regulator, becoming the first treatment for the condition to receive the nod in more than 40 years.<\/p>\n

The company expects to launch the drug, Nereus, in the coming months.<\/p>\n

Sign up here.<\/a><\/p>\n

Motion-induced vomiting is a response triggered by mixed signals between the eyes, inner ear and body sensors, during activities such as boating, driving or flying.<\/p>\n

The U.S. Food and Drug Administration’s approval was based on two late-stage studies with a total of 681 patients, in which the drug, also known as tradipitant, had significantly reduced vomiting.<\/p>\n

It works by blocking a brain receptor linked to nausea and vomiting.<\/p>\n

“Sales of tradipitant solely in this indication could exceed $100 million annually at peak in the U.S. alone,” said H.C. Wainwright analyst Raghuram Selvaraju.<\/p>\n

Other approved treatments to prevent motion sickness are Viatris’ (VTRS.O), opens new tab<\/a> prescription scopolamine patch, Transderm Scop, WellSpring Pharmaceutical’s Bonine and Prestige Consumer Healthcare’s (PBH.N), opens new tab<\/a> Dramamine.<\/p>\n

The FDA had originally placed a partial clinical hold on Vanda’s tradipitant in December 2018, citing the need for additional six-month chronic toxicity studies in dogs due to the classification of motion sickness as a chronic condition.<\/p>\n

The agency lifted the clinical hold on December 4, calling motion sickness an acute condition and dropping the study requirement.<\/p>\n

Vanda licensed tradipitant from Eli Lilly (LLY.N), opens new tab<\/a> in 2012 and has been testing it for several uses, including motion sickness, a stomach disorder called gastroparesis, and nausea caused by certain diabetes drugs.<\/p>\n

The company did not immediately respond to a Reuters request for a comment on the drug’s pricing.<\/p>\n

Reporting by Siddhi Mahatole and Puyaan Singh in Bengaluru; Editing by Shilpi Majumdar<\/p>\n

Our Standards: The Thomson Reuters Trust Principles., opens new tab<\/a><\/p>\n

Purchase Licensing Rights<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"Dec 30 (Reuters) – Vanda Pharmaceuticals (VNDA.O), opens new tab said on Tuesday its drug for the prevention…\n","protected":false},"author":2,"featured_media":382992,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[33],"tags":[204275,64,63,205941,205942,86319,204785,205943,204802,205957,205956,205955,97932,205953,205954,205944,137,205945,23020,490,205946,205947,204793,205937,57247,205948,205949,204790,205950,204801,205951,205940,205938,101308,205952,205939,2489],"class_list":["post-382991","post","type-post","status-publish","format-standard","has-post-thumbnail","category-medication","tag-amers","tag-au","tag-australia","tag-bact","tag-biodrg","tag-biz","tag-cmpny","tag-cprod","tag-destlita","tag-destohlt","tag-destousdnm","tag-destoushem","tag-gen","tag-govact","tag-govadm","tag-hea","tag-health","tag-heca","tag-legal","tag-medication","tag-medreg","tag-mrch","tag-namer","tag-nrlpaohlt","tag-phar","tag-phar1","tag-phmr","tag-publ","tag-regs","tag-reuters-legal","tag-rhpiapprovals","tag-rhpiregulatory","tag-rsbiregulatory-oversight","tag-sci","tag-topicpharma-healthcare-business-health","tag-topicpharma-healthcare-policy-regulation","tag-us"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/382991","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/comments?post=382991"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/382991\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media\/382992"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media?parent=382991"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/categories?post=382991"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/tags?post=382991"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}