{"id":416018,"date":"2026-01-16T03:37:09","date_gmt":"2026-01-16T03:37:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/au\/416018\/"},"modified":"2026-01-16T03:37:09","modified_gmt":"2026-01-16T03:37:09","slug":"have-australian-researchers-discovered-the-secret-to-treating-sepsis","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/au\/416018\/","title":{"rendered":"Have Australian researchers discovered the secret to treating sepsis?"},"content":{"rendered":"<p><img alt=\"Have Australian researchers discovered the secret to treating sepsis?\" class=\"lazyload img-thumbnail img-right\" data-original=\"https:\/\/d1v1e13ebw3o15.cloudfront.net\/data\/91705\/pool_and_spa_master\/..jpg\" title=\"Have Australian researchers discovered the secret to treating sepsis?\"\/><\/p>\n<p>Affecting millions of hospitalised patients across the world each year, sepsis occurs when the body\u2019s immune response to an infection attacks and injures its own tissues and organs.\u00a0Now, after promising results from a Phase 2 clinical trial in China of a sepsis drug candidate, <a href=\"https:\/\/www.griffith.edu.au\" rel=\"nofollow noopener\" target=\"_blank\">Griffith University<\/a> researchers are looking to progress to a Phase 3 trial; the drug of which, in the words of one of its co-developers \u2014 <a href=\"https:\/\/experts.griffith.edu.au\/18853-mark-von-itzstein\" rel=\"nofollow noopener\" target=\"_blank\">Distinguished Professor Mark von Itzstein AO<\/a> \u2014 is believed to hold the potential for \u201csaving millions of lives\u201d.<\/p>\n<p><img decoding=\"async\" alt=\"\" class=\"img-responsive\" src=\"https:\/\/www.newsbeep.com\/au\/wp-content\/uploads\/2026\/01\/Glycomics-2021-LM-7186_Mark.jpg.jpg\" style=\"display: block; margin: auto\"\/><\/p>\n<p style=\"text-align:center\">Distinguished Professor Mark von Itzstein AO. Source: Griffith University<\/p>\n<p>The drug, STC3141, is carbohydrate-based and was developed by von Itzstein and his team from Griffith\u2019s <a href=\"https:\/\/www.griffith.edu.au\/research\/institute-biomedicine-glycomics\" rel=\"nofollow noopener\" target=\"_blank\">Institute for Biomedicine and Glycomics<\/a>, and <a href=\"https:\/\/jcsmr.anu.edu.au\/people\/emeritus-professor-christopher-parish\" rel=\"nofollow noopener\" target=\"_blank\">Professor Christopher Parish<\/a> and his team at the <a href=\"https:\/\/www.anu.edu.au\" rel=\"nofollow noopener\" target=\"_blank\">Australian National Universi<\/a>ty. \u201cThe trial met the key endpoints to indicate the drug candidate was successful in reducing sepsis in humans,\u201d von Itzstein said.<\/p>\n<p>Administered as an infusion via a cannula, STC3141 was found to counteract a significant biological molecule release phenomenon, which occurred in the body during the course of sepsis \u2014 the small-molecule experimental drug serving as a potential treatment for sepsis by reversing organ damage.<\/p>\n<p>The Phase 2 trial was conducted by Grand Pharmaceutical Group Limited (<a href=\"https:\/\/www.grandpharma.cn\/en\/\" rel=\"nofollow noopener\" target=\"_blank\">Grand Pharma<\/a>) and involved 180 patients with sepsis. Grand Pharma would now look to progress to a Phase 3 trial, to continue testing the efficacy of the treatment and, von Itzstein said, with the hope that: \u201cwe could see the treatment reach the market in a handful [of] years, potentially saving millions of lives\u201d.<\/p>\n<p>Top image credit: iStock.com\/Artur Plawgo. Stock image used is for illustrative purposes only.<\/p>\n","protected":false},"excerpt":{"rendered":"Affecting millions of hospitalised patients across the world each year, sepsis occurs when the body\u2019s immune response to&hellip;\n","protected":false},"author":2,"featured_media":416019,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[219521,64,63,219524,219522,219525,219519,219518,137,110149,219526,219520,219523],"class_list":{"0":"post-416018","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-anti-sepsis-therapy","9":"tag-au","10":"tag-australia","11":"tag-carbohydrate-based-drug","12":"tag-drug-candidate","13":"tag-drug-trial","14":"tag-grand-pharma","15":"tag-grand-pharmaceutical-group-limited","16":"tag-health","17":"tag-sepsis","18":"tag-sepsis-drug-trial","19":"tag-sepsis-treatment","20":"tag-stc3141"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/416018","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/comments?post=416018"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/416018\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media\/416019"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media?parent=416018"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/categories?post=416018"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/tags?post=416018"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}