{"id":62230,"date":"2025-08-12T09:47:19","date_gmt":"2025-08-12T09:47:19","guid":{"rendered":"https:\/\/www.newsbeep.com\/au\/62230\/"},"modified":"2025-08-12T09:47:19","modified_gmt":"2025-08-12T09:47:19","slug":"ed-esplin-real-world-evidence-supports-shift-to-universal-genetic-testing-in-breast-cancer-care","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/au\/62230\/","title":{"rendered":"Ed Esplin: Real-World Evidence Supports Shift to Universal Genetic Testing in Breast Cancer Care"},"content":{"rendered":"<p>Ed Esplin, Clinical Geneticist and Medical Officer of Invitae, shared a post on <a href=\"https:\/\/x.com\/EdEsplin\/status\/1954555604288278827\" rel=\"nofollow\">X<\/a> about a paper he co-authored with colleagues, published in JAMA Network Open:<\/p>\n<p>\u201cOur study provides RWE that universal genetic testing, per the American Society of Breast Surgeons (ASBrS), can identify patients with actionable PGMs who are missed under the currently published NCCN criteria\u2026<\/p>\n<p>Highlights the utility of a universal testing approach in breast cancer care\u2026 supports a shift from selective to universal (germline testing) in oncology \u2013 a transition that mirrors broader trends in precision medicine.\u201d<\/p>\n<p>Title: Clinical Utility of Universal Germline Genetic Testing for Patients With Breast Cancer<\/p>\n<p>Authors: Pat W. Whitworth, Peter D. Beitsch, Rakesh Patel, Barry Rosen, Gia Compagnoni, Paul L. Baron, Rache Simmons, Eric A. Brown, Linsey Gold, Dennis Holmes, Linda Ann Smith, Michael Kinney, Ian Grady, Patricia Clark, Karen Barbosa, Samuel Lyons, Lee Riley, Cynara Coomer, Lisa Curcio, Antonio Ruiz, Sadia Khan, Heather MacDonald, Kevin Hughes, Mary Kay Hardwick, Brandie Heald, Sandra B. Munro, Sarah M. Nielsen, Edward D. Esplin<\/p>\n<p>You can read the <a href=\"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2796613\" target=\"_blank\" rel=\"noopener nofollow\">Full Article<\/a> on JAMA Network Open.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/au\/wp-content\/uploads\/2025\/08\/Screenshot-2025-08-12-015749-800x374.png\" alt=\"Ed Esplin: Real-World Evidence Supports Shift to Universal Genetic Testing in Breast Cancer Care\" title=\"Ed Esplin: Real-World Evidence Supports Shift to Universal Genetic Testing in Breast Cancer Care 1\"\/><\/p>\n<p>You also read:<\/p>\n<p>\u201c<a href=\"https:\/\/link.springer.com\/article\/10.1245\/s10434-025-17939-w\" target=\"_blank\" rel=\"noopener nofollow\">Are Broadened Guidelines Improving our Detection of Pathologic Genetic Mutations in Breast Cancer Patients? A 5-Year Comparative Analysis of American Society of Breast Surgeons and National Comprehensive Cancer Network Guidelines<\/a>\u201d<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/au\/wp-content\/uploads\/2025\/08\/Screenshot-2025-08-12-015915-800x468.png\" alt=\"Ed Esplin: Real-World Evidence Supports Shift to Universal Genetic Testing in Breast Cancer Care\" title=\"Ed Esplin: Real-World Evidence Supports Shift to Universal Genetic Testing in Breast Cancer Care 2\"\/><\/p>\n<p>\u201c<a href=\"https:\/\/ascopubs.org\/doi\/10.1200\/JCO.18.01631\" target=\"_blank\" rel=\"noopener nofollow\">Underdiagnosis of Hereditary Breast Cancer: Are Genetic Testing Guidelines a Tool or an Obstacle<\/a>?\u201d<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/au\/wp-content\/uploads\/2025\/08\/Screenshot-2025-08-12-015924-800x266.png\" alt=\"Ed Esplin: Real-World Evidence Supports Shift to Universal Genetic Testing in Breast Cancer Care\" title=\"Ed Esplin: Real-World Evidence Supports Shift to Universal Genetic Testing in Breast Cancer Care 3\"\/><\/p>\n<p>\u201c<a href=\"https:\/\/ascopubs.org\/doi\/10.1200\/JCO.22.02833\" target=\"_blank\" rel=\"noopener nofollow\">Universal Germline and Tumor Genomic Testing Needed to Win the War Against Cancer: Genomics Is the Diagnosis<\/a>\u201d<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/au\/wp-content\/uploads\/2025\/08\/Screenshot-2025-08-12-015935-800x193.png\" alt=\"Ed Esplin: Real-World Evidence Supports Shift to Universal Genetic Testing in Breast Cancer Care\" title=\"Ed Esplin: Real-World Evidence Supports Shift to Universal Genetic Testing in Breast Cancer Care 4\"\/><\/p>\n<p>More posts featuring <a href=\"https:\/\/oncodaily.com\/tag\/ed-esplin\" rel=\"nofollow noopener\" target=\"_blank\">Ed Esplin<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"Ed Esplin, Clinical Geneticist and Medical Officer of Invitae, shared a post on X about a paper he&hellip;\n","protected":false},"author":2,"featured_media":62231,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[64,63,336,128],"class_list":["post-62230","post","type-post","status-publish","format-standard","has-post-thumbnail","category-genetics","tag-au","tag-australia","tag-genetics","tag-science"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/62230","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/comments?post=62230"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/62230\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media\/62231"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media?parent=62230"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/categories?post=62230"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/tags?post=62230"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}