{"id":631268,"date":"2026-04-26T03:48:11","date_gmt":"2026-04-26T03:48:11","guid":{"rendered":"https:\/\/www.newsbeep.com\/au\/631268\/"},"modified":"2026-04-26T03:48:11","modified_gmt":"2026-04-26T03:48:11","slug":"scientists-cured-type-1-diabetes-in-mice-in-breakthrough-study","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/au\/631268\/","title":{"rendered":"Scientists Cured Type-1 Diabetes in Mice in Breakthrough Study"},"content":{"rendered":"<p data-path-to-node=\"0\">Researchers at Stanford Medicine have found a way to potentially cure Type 1 diabetes using a new transplant method. In a recent study involving mice, the team successfully combined blood stem cells with pancreatic islet cells from a donor. The mice were cured of the disease and didn\u2019t need insulin or anti-rejection drugs for the rest of the six-month experiment.<\/p>\n<p data-path-to-node=\"1\">Type 1 <a href=\"https:\/\/www.tomorrowsworldtoday.com\/health-and-wellness\/how-ai-digital-twins-are-coding-the-end-of-type-2-diabetes\/\" rel=\"nofollow noopener\" target=\"_blank\">diabetes<\/a> happens because the immune system accidentally attacks the body\u2019s own insulin-producing cells. This new approach fixes that by creating a \u201chybrid\u201d immune system that includes cells from both the donor and the patient. This prevents the body from attacking the new transplant and stops the original autoimmune attack in its tracks.<\/p>\n<p>A Safer Way to Treat Type-1 Diabetes<br \/>\n<img fetchpriority=\"high\" decoding=\"async\" title=\"type-1 diabetes\" alt=\"type-1 diabetes\" width=\"1920\" height=\"1080\"  src=\"https:\/\/www.newsbeep.com\/au\/wp-content\/uploads\/2026\/04\/type-1-diabetes-1.png\" data- class=\"wp-image-52395 size-full lazyload\"\/>Photo: Michail Petrov\/Shutterstock<\/p>\n<p data-path-to-node=\"3\">One of the biggest hurdles for transplants is the demanding prep work. Usually, patients need high doses of radiation to \u201cclear space\u201d for new cells, which can cause serious side effects like infertility. However, the Stanford team found a way to dial the radiation down, adding specific drugs to the mix. As a result, they reduced the radiation dose from 225 cGy to just 10 cGy.<\/p>\n<p data-path-to-node=\"4\">\u201cBringing radiation doses down to a level that carries minimal clinical risk dramatically reduces barriers to achieving immune tolerance and curing diabetes,\u201d <a href=\"https:\/\/www.eurekalert.org\/news-releases\/1125525\" target=\"_blank\" rel=\"noopener nofollow\">said postdoctoral scholar<\/a> Stephan Ramos, PhD. \u201cThis gentler preconditioning regimen also opens the door to using similar strategies in a much broader range of patients and diseases than was previously feasible.\u201d<\/p>\n<p>Why this matters<\/p>\n<p data-path-to-node=\"6\">The method doesn\u2019t just replace missing cells; it \u201cre-educates\u201d the immune system. This means the body learns to accept the new islet cells as friends rather than enemies.<\/p>\n<p data-path-to-node=\"7\">\u201cThe possibility of translating these findings into humans is very exciting,\u201d said Seung K. Kim, MD, PhD. \u201cThe key steps in our study \u2014 which result in animals with a hybrid immune system containing cells from both the donor and the recipient \u2014 are already being used in the clinic for other conditions. We believe this approach will be transformative for people with Type 1 diabetes or other autoimmune diseases, as well as for those who need solid organ transplants.\u201d<\/p>\n<p data-path-to-node=\"8\">There is still work to do, like finding enough donor cells for human patients, but the researchers are optimistic. This \u201cgentle\u201d transplant method could eventually help people with other conditions, too, like lupus or<a href=\"https:\/\/www.tomorrowsworldtoday.com\/health-and-wellness\/first-vagus-nerve-device-for-rheumatoid-arthritis-gets-federal-approval\/\" rel=\"nofollow noopener\" target=\"_blank\"> rheumatoid arthritis<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"Researchers at Stanford Medicine have found a way to potentially cure Type 1 diabetes using a new transplant&hellip;\n","protected":false},"author":2,"featured_media":631269,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[64,63,137,337,42119],"class_list":["post-631268","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-au","tag-australia","tag-health","tag-research","tag-world-of-innovation"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/631268","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/comments?post=631268"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/631268\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media\/631269"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media?parent=631268"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/categories?post=631268"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/tags?post=631268"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}