{"id":666445,"date":"2026-05-12T17:28:22","date_gmt":"2026-05-12T17:28:22","guid":{"rendered":"https:\/\/www.newsbeep.com\/au\/666445\/"},"modified":"2026-05-12T17:28:22","modified_gmt":"2026-05-12T17:28:22","slug":"health-check-for-bloodied-csl-the-horror-continues","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/au\/666445\/","title":{"rendered":"Health Check: For bloodied CSL, the horror continues"},"content":{"rendered":"<p>For the battered and bloodied CSL, the problems look like getting worse before things get better. Pic: Getty Images.<\/p>\n<p>Despite \u201cgreen shoots\u201d of recovery, CSL\u2019s earnings officially are going backwards<br \/>\nEmvision eyes a two-year time saving with expanded pivotal stroke trial<br \/>\nNow out of favour with Trump, Marty Makary is polishing off his CV<\/p>\n<p>\u00a0<\/p>\n<p>In today\u2019s thumping profit downgrade, blood and plasma giant <a href=\"https:\/\/stockhead.com.au\/company\/csl-csl\/\" rel=\"nofollow noopener\" target=\"_blank\">CSL (ASX:CSL)<\/a> admits its current year earnings will go backwards, as management strives to right the listing ship.<\/p>\n<p>Despite the company\u2019s woes, management in February pointed to underlying net profit advancing 4-7%.<\/p>\n<p>Now it looks like earnings for the year to June 30 2025 will retreat around 4%.<\/p>\n<p>Concerningly, the core Behring arm faces improved competitor capacity that has boosted excess plasma supply.<\/p>\n<p>This problem appears to be structural, rather than cyclical.<\/p>\n<p>Investors slashed CSL shares by as much as 20%, pushing them below the $100 mark for the first time in ten years.<\/p>\n<p>\u201cWe fully recognise that CSL\u2019s financial outcomes have fallen short of expectations,\u201d interim CEO Gordon Naylor said.<\/p>\n<p>He said the company\u2019s US$32 billion ($44bn) of invested capital clearly was not all \u201cworking as hard as it should be\u201d.<\/p>\n<p>Naylor said management\u2019s growth medicine was helping, \u201cbut the financial benefits will take longer than previously anticipated to materialise\u201d.<\/p>\n<p>The company said immunoglobulin demand in its core US market was growing at mid to high single digits, consistent with CSL\u2019s expectations.<\/p>\n<p>But the reported revenue will reflect CSL\u2019s \u201cnormalisation of channel inventory\u201d.<\/p>\n<p>In other words, there was too much stuff in the system.<\/p>\n<p>\u00a0<\/p>\n<p>What\u2019s the damage?<\/p>\n<p>CSL now expects full-year revenue of US$15.2 billion, around 2% lower and net profit after tax and amortisation (NPATA) of US$3.1bn (4% lower).<\/p>\n<p>This is on a \u2018constant currency\u2019 basis. Taking \u201cvolatile\u201d currencies into account, revenue will come in US$400m higher, while NPATA \u00a0will be a modest US$30m lower.<\/p>\n<p>But management always has nominated constant currency as its preferred measure.<\/p>\n<p>The immunoglobulin problem is expected to result in a US$300m revenue hit.<\/p>\n<p>Turnover will decline by a further US$200m because of the declining value of the Chinese albumin market (despite CSL\u2019s expanding share).<\/p>\n<p>And did anyone mention the Middle East conflict?<\/p>\n<p>The conflagration will erase US$150m of revenue from the iron side of the business and CSL\u2019s haemophilia treatment Hemgenix.<\/p>\n<p>\u00a0<\/p>\n<p>Green shoots among the weeds<\/p>\n<p>More positively note, management reports \u201cgreen shoots\u201d, including \u201cimprovements in end-patient demand and momentum across recent product launches\u201d.<\/p>\n<p>Behring\u2019s second half volumes have grown, although gross margins have \u201cdegraded\u201d.<\/p>\n<p>The performance of CSL\u2019s flu vaccine arm also has been \u201cmoderately stronger than previously anticipated\u201d.<\/p>\n<p>On Behring, Naylor said the industry was \u201cstable and growing and the company has evident strengths in plasma collections and influenza vaccines\u201d.<\/p>\n<p>Naylor said CSL remained \u201cvery profitable\u201d, with \u201cmetronomic\u201d cash flows and significant financial capacity.<\/p>\n<p>\u201cI can also say that CSL continues to have evident competitive strengths in plasma collection and influenza vaccines.\u201d<\/p>\n<p>In its transformation program already announced, CSL expects ongoing annual cost savings of US$500-550m.<\/p>\n<p>CSL today also flagged US$5bn of non-cash asset impairments over the next two years, US$1.5bn of which was recognised in the December 2025 (first) half.<\/p>\n<p>\u00a0<\/p>\n<p>Emvision expands its stroke trial remit<\/p>\n<p>The developer of a portable stroke detection unit, <a href=\"https:\/\/stockhead.com.au\/company\/emvision-medical-devices-emv\/\" rel=\"nofollow noopener\" target=\"_blank\">EMvision Medical Devices (ASX:EMV)<\/a> has expanded its pivotal trial to the dominant majority of strokes.<\/p>\n<p>The study will now test the ability of the company\u2019s Emu device to detect acute ischaemic strokes (blockages). This is opposed to the original remit of identifying haemorrhagic strokes (bleeds).<\/p>\n<p>\u201cAn ischaemia detection feature extends the device\u2019s clinically actionable use case in the dominant majority (around 80%) of stroke presentations,\u201d the company said.<\/p>\n<p>\u201cBecause ischaemic stroke interventions (clot dissolving drugs and clot retrieval) are highly time-dependent, the ability to rapidly identify ischaemia at the bedside has the potential to meaningfully reduce intervention delays and improve patient outcomes.\u201d<\/p>\n<p>The company said acute ischaemic stroke detection is widely recognised as a more complex clinical and technical problem than haemorrhage detection.<\/p>\n<p>This was especially the case in \u201chyperacute window and in care settings where advanced multimodal neuroimaging is not immediately available\u201d.<\/p>\n<p>Meanwhile, the company says the Emu trial is up and striding across eight US and Australian hospitals, with more 125 patients enrolled so far.<\/p>\n<p>\u201cThe device continues to integrate seamlessly into hospital code stroke workflows, with no device-related adverse events reported.\u201d<\/p>\n<p>The company intends to engage with the FDA on the proposed expanded endpoints, which will avail of the same patients and infrastructure.<\/p>\n<p>Management believes its approach could save up to two years and many millions of dollars,\u00a0 relative to carrying out a standalone ischaemia trial later on.<\/p>\n<p>\u00a0<\/p>\n<p>Pacific Edge raises funds amid deeper losses<\/p>\n<p>Bladder cancer test developer <a href=\"https:\/\/stockhead.com.au\/company\/pacific-edge-peb\/\" rel=\"nofollow noopener\" target=\"_blank\">Pacific Edge (ASX:PEB)<\/a> is doing the rounds to raise $NZ24 million ($19.6m) in a placement and retail issue.<\/p>\n<p>Pacific Edge has been tussling with US reimbursement gatekeepers over coverage of its Cxbladder assay.<\/p>\n<p>Thus, the funding is to ensure Pacific Edge has the \u201cresources and capacity\u201d to regain the crucial US Medicare coverage and \u201cposition the business for growth\u201d.<\/p>\n<p>The placement seeks to raise $NZ18m with a further $NZ6m from the retail stanza which is akin to a share purchase plan.<\/p>\n<p>Both are priced at NZ17 cents a share, a modest 2.3% discount to today\u2019s frozen price.<\/p>\n<p>Ahead of its May 26 full year result, Pacific Edge also said the coverage removal resulted in revenue falling to $NZ11.5 million, from $NZ21.8m previously.<\/p>\n<p>This increased the net loss to NZ$35.7m, from NZ$29.9m previously.<\/p>\n<p>\u00a0<\/p>\n<p>Dead man walking at FDA<\/p>\n<p>According to multiple US reports, President Trump will fire his choice pick as head of the FDA on Monday.<\/p>\n<p>It looks like FDA Commissioner Marty Makary offended too many parties, ranging from vaping advocates, the anti-abortion lobby and Big Pharma.<\/p>\n<p>Trump reportedly ticked off Makary for refusing to approve fruit-flavored vapes.<\/p>\n<p>Most interestingly, Makary appears to have gone too far on the anti-vaccine front by blocking material showing shingles and Covid vaccines to be safe.<\/p>\n<p>Throw in concerns about a proposed easier drug approval approval route from two late-stage clinical studies to one and Makary\u2019s job looks as safe as Keir Starmer\u2019s.<\/p>\n<p>At least some Australian biotech figures thought the agency had settled down since Trump\u2019s early days. But it looks like still waters run deep.<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>At Stockhead we tell it as it is. While Emvision is a Stockhead advertiser, the company did not sponsor this article.<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"For the battered and bloodied CSL, the problems look like getting worse before things get better. Pic: Getty&hellip;\n","protected":false},"author":2,"featured_media":666446,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[64,63,137,500],"class_list":["post-666445","post","type-post","status-publish","format-standard","has-post-thumbnail","category-healthcare","tag-au","tag-australia","tag-health","tag-healthcare"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/666445","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/comments?post=666445"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/666445\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media\/666446"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media?parent=666445"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/categories?post=666445"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/tags?post=666445"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}