{"id":674797,"date":"2026-05-16T13:49:23","date_gmt":"2026-05-16T13:49:23","guid":{"rendered":"https:\/\/www.newsbeep.com\/au\/674797\/"},"modified":"2026-05-16T13:49:23","modified_gmt":"2026-05-16T13:49:23","slug":"mlb-predictions-and-moneyline-picks-for-saturday-may-16","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/au\/674797\/","title":{"rendered":"MLB Predictions and Moneyline Picks for Saturday, May 16"},"content":{"rendered":"

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A full 15-game slate awaits, and we have 15 moneyline picks throughout the day for you to consider.<\/p>\n

We’ve found solid matchups with good odds and a nice opportunity for you to grow your bankroll.\u00a0\u00a0<\/p>\n

Find out more in my MLB picks<\/a> for Saturday, May 16.<\/p>\n

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MLB moneyline picks for May 16<\/p>\n

Matchup<\/p>\n

Pick<\/p>\n

Blue Jays<\/a>
vs
Tigers<\/a><\/p>\n

-108<\/p>\n

Royals
vs
Cardinals<\/a><\/p>\n

-113<\/p>\n

Diamondbacks<\/a>
vs
Rockies<\/a><\/p>\n

-117<\/p>\n

Orioles<\/a>
vs
Nationals<\/p>\n

-113<\/p>\n

Phillies<\/a>
vs
Pirates<\/p>\n

+117<\/p>\n

Marlins<\/a>
vs
Rays<\/a><\/p>\n

+122<\/p>\n

Reds<\/a>
vs
Guardians<\/p>\n

+150<\/p>\n

Cubs<\/a>
vs
White Sox<\/a><\/p>\n

-104<\/p>\n

Brewers<\/a>
vs
Twins<\/p>\n

-108<\/p>\n

Rangers
vs
Astros<\/p>\n

-104<\/p>\n

Red Sox<\/a>
vs
Braves<\/p>\n

+117<\/p>\n

Yankees<\/a>
vs
Mets<\/a><\/p>\n

+108<\/p>\n

Padres
vs
Mariners<\/a><\/p>\n

-133<\/p>\n

Dodgers<\/a>
vs
Angels<\/p>\n

-138<\/p>\n

Giants
vs
Athletics<\/p>\n

-127<\/p>\n

Prices courtesy of Polymarket as of 5-15.<\/p>\n

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Expert MLB moneyline picks for May-16Blue Jays vs Tigers: Tigers (-108)<\/p>\n

Tigers win probability: 52%<\/p>\n

Detroit<\/a> gets the nod at home, where its relievers have been more reliable than Toronto<\/a>‘s over the last two weeks.\u00a0<\/p>\n

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This is a coin flip with a home-field tiebreaker, and if this game is close late, the Tigers are the team to back.<\/p>\n

Royals vs Cardinals: Cardinals (-113)<\/p>\n

Cardinals win probability: 53%<\/p>\n

St. Louis<\/a> is seven games better than Kansas City<\/a> in the standings and opens this series at home.<\/p>\n

Kyle Leahy<\/a> gets the ball against Noah Cameron<\/a>, and the Cardinals\u2019 lineup has been productive at Busch Stadium all season.<\/p>\n

Diamondbacks vs Rockies: Diamondbacks (-117)<\/p>\n

Diamonbacks win probability: 53.9%<\/p>\n

Although Arizona<\/a>‘s lineup has been ice cold lately,\u00a0the Rockies are 17-27 and (once again) one of the worst teams in baseball.\u00a0<\/p>\n

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Their pitching has been getting shelled all season, and Eduardo Rodriguez<\/a> gives Arizona a real advantage on the mound.\u00a0<\/p>\n

Phillies vs Pirates: Pirates (+117)<\/p>\n

Pirates win probability: 46%<\/p>\n

Pittsburgh<\/a>‘s lineup has been the hottest in baseball over the last two weeks, and the Pirates own a better record than Philadelphia<\/a>.\u00a0<\/p>\n

With Bubba Chandler<\/a> taking the mound at PNC Park, the Buccos get the nod.\u00a0<\/p>\n

Orioles vs Nationals: Nationals (-113)<\/p>\n

Nationals win probability: 53%<\/p>\n

Washington<\/a>‘s lineup has been one of the hottest in the NL over the last two weeks, while Baltimore<\/a>‘s offense is among the coldest.<\/p>\n

The Nationals’ hitting edge is significant enough to back the home team.<\/p>\n

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Marlins vs Rays: Marlins (+122)<\/p>\n

Marlins win probability: 45%<\/p>\n

Miami<\/a>\u2019s bullpen has been genuinely stingy lately, and Sandy Alcantara<\/a> vs. Nick Martinez<\/a> sets up a real pitching duel.<\/p>\n

The Marlins aren\u2019t getting blown out here, and that\u2019s enough to make them worth a look.<\/p>\n

Reds vs Guardians: Reds (+150)<\/p>\n

Reds win probability: 40%<\/p>\n

Cincinnati<\/a>‘s lineup isn’t far behind Cleveland<\/a>‘s recent production, and Chris Paddack<\/a> gives the Reds tremendous value at this price.\u00a0<\/p>\n

Rangers vs Astros: Rangers (-104)<\/p>\n

Rangers win probability: 51%<\/p>\n

Houston<\/a> is 17-28, and its lineup has been among the least productive in the American League recently. Jacob deGrom<\/a> starting for Texas<\/a> against Kai-Wei Teng<\/a> is the entire argument. <\/p>\n

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Getting a pitcher of deGrom’s caliber at essentially even money against a struggling team is a straightforward play.<\/p>\n

Cubs vs White Sox: White Sox (-104)<\/p>\n

White Sox win probability: 51%<\/p>\n

The White Sox have been one of the hottest offensive teams in baseball over the last two weeks, while the Cubs’ lineup has gone quiet.\u00a0<\/p>\n

For the first time in a while, the South Side has life in this Windy City rivalry.<\/p>\n

Brewers vs Twins: Brewers (-108)<\/p>\n

Brewers win probability: 52%<\/p>\n

Milwaukee<\/a>\u2019s relievers have been among the best in baseball lately, and they now face a Twins team whose biggest weakness is the bullpen.<\/p>\n

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Despite Minnesota<\/a> getting Royce Lewis<\/a> back from the IL, that’s not going to prevent them from blowing games in late-inning situations.<\/p>\n

Padres vs Mariners: Mariners (-133)<\/p>\n

Mariners win probability: 57%<\/p>\n

San Diego<\/a>‘s lineup has been one of the two coldest offenses in baseball lately. <\/p>\n

Logan Gilbert<\/a> is one of the better pitchers in the AL and gets to face that dormant lineup at home. <\/p>\n

The price is steep, but the Mariners are worth the price.<\/p>\n

Red Sox vs Braves: Red Sox (+117)<\/p>\n

Red Sox win probability: 46%<\/p>\n

Boston<\/a>‘s bullpen has been one of the best in the sport recently, and rookie starter Payton Tolle<\/a> has proven to be no slouch either.<\/p>\n

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The Red Sox are a live underdog with real teeth.<\/p>\n

Yankees vs Mets: Mets (+108)<\/p>\n

Mets win probability: 47%<\/p>\n

The New York Yankees’ lineup has been one of the best in baseball lately, but Carlos Rodon<\/a> has been unreliable, and the Mets’ bullpen has been sharper than the Yankees’ recently. <\/p>\n

With Mendoza reportedly on the hot seat, the stakes of the Stadium Series at Citi Field add even more urgency. The home team at nearly even money is worth backing.<\/p>\n

Dodgers vs Angels: Dodgers (-138)<\/p>\n

Dodgers win probability: 58%<\/p>\n

The Angels possess one of the coldest lineups in baseball over the last two weeks. Meanwhile, the Dodgers have a deeper, more talented roster top to bottom, and their bullpen has been sharp lately.\u00a0<\/p>\n

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Take the defending champs to pull away in Anaheim.\u00a0<\/p>\n

Giants vs Athletics: Athletics (-127)<\/p>\n

Athletics win probability: 55.7%<\/p>\n

San Francisco<\/a>‘s bullpen has been the worst in baseball over the last two weeks, and the Giants’ lineup hasn’t fared much better.\u00a0<\/p>\n

The A\u2019s offense continues to take the league by storm, and Luis Severino<\/a> should deliver a solid start in this Northern California battle.<\/p>\n

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.<\/p>\n

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This article originally appeared on Covers.com<\/a>, read the full article here<\/a> and view our best betting sites<\/a> or check out our top sportsbook promos<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"Want to get more Covers content? Add us as a preferred source on your Google account here. A…\n","protected":false},"author":2,"featured_media":674798,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[558],"tags":[5888,64,63,613,12642,483,5131,66395,16089,91954,33567,10027,6115,5128,39616,12266,7809,5138,77921,5145,45519,13521,292628,112677,161138,5143,5141,5144,5140,5130,5387,591,178750,14541,5129,76377,5136,5137,5132,2274,16088,13506,25104,205258,5886,6113,39618,85,5887,3370,13338,3920,3601,23871,292627,6114],"class_list":["post-674797","post","type-post","status-publish","format-standard","has-post-thumbnail","category-mlb","tag-arizona","tag-au","tag-australia","tag-baltimore","tag-blue-jays","tag-boston","tag-brewers","tag-bubba-chandler","tag-cardinals","tag-carlos-rodon","tag-chris-paddack","tag-cincinnati","tag-cleveland","tag-cubs","tag-degrom","tag-detroit","tag-diamondbacks","tag-dodgers","tag-eduardo-rodriguez","tag-houston","tag-kai-wei-teng","tag-kansas-city","tag-kyle-leahy","tag-logan-gilbert","tag-luis-severino","tag-mariners","tag-marlins","tag-mets","tag-miami","tag-milwaukee","tag-minnesota","tag-mlb","tag-nick-martinez","tag-noah-cameron","tag-orioles","tag-payton-tolle","tag-philadelphia","tag-phillies","tag-pittsburgh","tag-rays","tag-red-sox","tag-reds","tag-rockies","tag-royce-lewis","tag-san-diego","tag-san-francisco","tag-sandy-alcantara","tag-sports","tag-st-louis","tag-texas","tag-tigers","tag-toronto","tag-washington","tag-white-sox","tag-win-probability","tag-yankees"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/674797","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/comments?post=674797"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/674797\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media\/674798"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media?parent=674797"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/categories?post=674797"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/tags?post=674797"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}