{"id":676929,"date":"2026-05-17T15:14:08","date_gmt":"2026-05-17T15:14:08","guid":{"rendered":"https:\/\/www.newsbeep.com\/au\/676929\/"},"modified":"2026-05-17T15:14:08","modified_gmt":"2026-05-17T15:14:08","slug":"padres-vs-mariners-odds-prediction-line-2026-mlb-picks-for-sunday-night-baseball","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/au\/676929\/","title":{"rendered":"Padres vs. Mariners odds, prediction, line: 2026 MLB picks for Sunday Night Baseball"},"content":{"rendered":"

An interleague matchup on MLB Rivalry Weekend has the Seattle Mariners<\/a> hosting the San Diego Padres<\/a> on ‘Sunday Night Baseball’. Seattle (22-25) has dropped the first two games of this series, including a 7-4 defeat on Saturday. San Diego (27-18) is seeking its first three-game winning streak since April 18-21. George Kirby<\/a> (5-2, 2.84 ERA) will take the ball for the Mariners, countered by Lucas Giolito<\/a>, who will make his first appearance of the season after going 10-4 last year with Boston.<\/p>\n

First pitch is at 7:20 p.m. ET from T-Mobile Park in Seattle. The Padres have defeated the Mariners in five straight dating back to last season. The latest Mariners vs. Padres odds list Seattle as the -162 favorite on the money line (risk $162 to win $100). The over\/under for total runs is 7.5. Before making any Padres vs. Mariners picks or MLB predictions, be sure to see the Sunday Night Baseball predictions and betting advice from SportsLine’s proven computer model<\/a>.\u00a0<\/p>\n

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The SportsLine Projection Model simulates every MLB game 10,000 times, and enters Week 8 on a 7-1 run on all top-rated MLB picks. It also excelled at making home run prop picks in 2025, returning nearly 30 units of profit. Anybody following its\u00a0MLB betting<\/a>\u00a0picks at\u00a0sportsbooks<\/a>\u00a0and on\u00a0betting sites<\/a>\u00a0could have seen strong returns.\u00a0 \u00a0\u00a0<\/p>\n

Now, the model has set its sights on Mariners vs. Padres<\/a> and just locked in its picks and MLB predictions.\u00a0You can head to SportsLine now to see the model’s picks<\/a>. Here are several\u00a0MLB odds<\/a>\u00a0and betting lines for Padres vs. Mariners:<\/p>\n

Mariners vs. Padres money line<\/p>\n

Mariners -162, Padres +135<\/p>\n

Mariners vs. Padres over\/under<\/p>\n

7.5 runs<\/p>\n

Mariners vs. Padres run line\u00a0<\/p>\n

Padres +1.5 (-163)<\/p>\n

Mariners vs. Padres picks<\/p>\n

See picks at SportsLine<\/a><\/p>\n

Mariners vs. Padres streaming\u00a0<\/p>\n

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Top Padres vs. Mariners predictions\u00a0<\/p>\n

After 10,000 simulations of Mariners vs. Padres, the model is going Over 7.5 total runs.\u00a0This will be Giolito’s first MLB game in nearly eight months, and he had an ERA of almost 5.00 across four minor league appearances this season. Thus, San Diego’s bullpen figures to be heavily worked, and bullpen-heavy games tend to be high-scoring ones. That was the case of Saturday’s matchup, which had nine total pitchers and hit the Over with 11 combined runs.<\/p>\n

As for Kirby, he’s coming off an outing in which he threw a season-low of 5 IP but gave up his second-most hits (7) and baserunners (9) of the season. Kirby has also been lit up by current Padres batters, allowing a .318 average (14 for 44) versus them. With concerns regarding both starting pitchers, the model forecasts 8.3 combined runs, making the Over a strong pick in\u00a0over\/under sports betting<\/a>. Get the Padres vs. Mariners money-line pick at SportsLine<\/a>.<\/p>\n

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How to make Mariners vs. Padres picks<\/p>\n

After simulating every pitch of Padres vs. Mariners 10,000 times, the model also says one side of the money line has all the value. You can get that pick at SportsLine<\/a>.\u00a0<\/p>\n

So who wins Mariners vs. Padres, and which side of the money line has all the value?\u00a0Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks<\/a>, and find out.<\/p>\n","protected":false},"excerpt":{"rendered":"An interleague matchup on MLB Rivalry Weekend has the Seattle Mariners hosting the San Diego Padres on ‘Sunday…\n","protected":false},"author":2,"featured_media":676930,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[558],"tags":[64,63,615,591,48834,9925,48836,326273,326274,326275,1189,5162,85,326276,326277],"class_list":["post-676929","post","type-post","status-publish","format-standard","has-post-thumbnail","category-mlb","tag-au","tag-australia","tag-betting","tag-mlb","tag-mlb-odds","tag-mlb-picks","tag-mlb-predictions","tag-padres-mariners-odds","tag-padres-mariners-picks","tag-padres-mariners-prediction","tag-san-diego-padres","tag-seattle-mariners","tag-sports","tag-sunday-night-baseball-picks","tag-sunday-night-baseball-prediction"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/676929","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/comments?post=676929"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/676929\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media\/676930"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media?parent=676929"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/categories?post=676929"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/tags?post=676929"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}