{"id":724350,"date":"2026-06-09T03:32:18","date_gmt":"2026-06-09T03:32:18","guid":{"rendered":"https:\/\/www.newsbeep.com\/au\/724350\/"},"modified":"2026-06-09T03:32:18","modified_gmt":"2026-06-09T03:32:18","slug":"mayo-clinic-study-shows-ai-can-reveal-brain-tumor-risks-without-costly-genetic-testing","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/au\/724350\/","title":{"rendered":"Mayo Clinic study shows AI can reveal brain tumor risks without costly genetic testing"},"content":{"rendered":"<p>Neurosciences<\/p>\n<p>June 8, 2026<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"576\" src=\"https:\/\/www.newsbeep.com\/au\/wp-content\/uploads\/2026\/06\/futuristic-medical-monitor-image-representing-technology-artificial-intelligence_1089540233-1024x576.webp\" alt=\"futuristic medical monitor image representing technology, artificial intelligence\" class=\"wp-image-316769\"  \/><\/p>\n<p class=\"wp-block-paragraph\">ROCHESTER, Minn. \u2014 <a href=\"https:\/\/mayoclinic.org?mc_id=us&amp;utm_source=newsnetwork&amp;utm_medium=l&amp;utm_campaign=mayoclinic&amp;geo=national&amp;placementsite=enterprise&amp;invsrc=other&amp;cauid=100721\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Mayo Clinic<\/a> researchers and collaborators have shown that artificial intelligence (AI) can analyze routine pathology slides to help classify <a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/meningioma\/symptoms-causes\/syc-20355643?mc_id=us&amp;utm_source=newsnetwork&amp;utm_medium=l&amp;utm_campaign=mayoclinic&amp;geo=national&amp;placementsite=enterprise&amp;invsrc=other&amp;cauid=100721\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">meningiomas<\/a>, the most common primary <a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/brain-tumor\/symptoms-causes\/syc-20350084?mc_id=us&amp;utm_source=newsnetwork&amp;utm_medium=l&amp;utm_campaign=mayoclinic&amp;geo=national&amp;placementsite=enterprise&amp;invsrc=other&amp;cauid=100721\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">brain tumor<\/a> in adults, and predict a patient&#8217;s risk of tumor recurrence.<\/p>\n<p class=\"wp-block-paragraph\">The study, <a href=\"https:\/\/www.thelancet.com\/journals\/landig\/article\/PIIS2589-7500(26)00009-9\/fulltext\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">published<\/a> in The Lancet Digital Health, demonstrates that deep learning models can extract molecular and prognostic information from standard hematoxylin and eosin, or H&amp;E, slides \u2014 the same type of tissue images already used in routine clinical care. These insights are typically obtained through DNA methylation profiling, an advanced genetic test which provides valuable diagnostic and prognostic information but can be costly, time-consuming and is unavailable in many hospitals.<\/p>\n<p class=\"wp-block-paragraph\">&#8220;This is one of the many studies where we can harness the strength of digital pathology by capturing the last two decades of genomic and molecular knowledge into AI algorithms,&#8221; says <a href=\"https:\/\/www.mayoclinic.org\/biographies\/zadeh-gelareh-m-d-ph-d\/bio-20574659?mc_id=us&amp;utm_source=newsnetwork&amp;utm_medium=l&amp;utm_campaign=mayoclinic&amp;geo=national&amp;placementsite=enterprise&amp;invsrc=other&amp;cauid=100721\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Gelareh Zadeh, M.D., Ph.D.<\/a>, chair of the Department of Neurologic Surgery at Mayo Clinic in Rochester and the David C. and Flora C. Pratt Distinguished Chief Medical Officer for <a href=\"https:\/\/www.mayoclinicplatform.org\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Mayo Clinic Platform<\/a>.<\/p>\n<p>Making advanced tumor insights more accessible<\/p>\n<p class=\"wp-block-paragraph\">Meningiomas can vary widely in behavior. Some grow slowly and may never return after treatment, while others are more aggressive and more likely to recur. Understanding that risk is critical for patients and care teams deciding whether additional treatment, such as <a href=\"https:\/\/www.mayoclinic.org\/tests-procedures\/radiation-therapy\/about\/pac-20385162?mc_id=us&amp;utm_source=newsnetwork&amp;utm_medium=l&amp;utm_campaign=mayoclinic&amp;geo=national&amp;placementsite=enterprise&amp;invsrc=other&amp;cauid=100721\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">radiation therapy<\/a>, may be needed after <a href=\"https:\/\/www.mayoclinic.org\/tests-procedures\/brain-tumor-surgery\/about\/pac-20584295?mc_id=us&amp;utm_source=newsnetwork&amp;utm_medium=l&amp;utm_campaign=mayoclinic&amp;geo=national&amp;placementsite=enterprise&amp;invsrc=other&amp;cauid=100721\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">surgery<\/a>.<\/p>\n<p class=\"wp-block-paragraph\">Molecular testing can help identify which tumors are more likely to recur and which may respond differently to treatment. But these tests require specialized technology and expertise, limiting access for many patients. <\/p>\n<p class=\"wp-block-paragraph\">Using tissue samples, pathology images and clinical data from 672 patients, researchers trained AI to uncover information about a tumor&#8217;s biology. Drawing on multiple de-identified datasets, including data resources from Mayo Clinic Platform, the models were able to classify meningioma subtypes and predict recurrence risk using standard pathology slides that are already part of routine patient care.<\/p>\n<p class=\"wp-block-paragraph\">The findings suggest that AI could one day help clinicians obtain more detailed tumor information without requiring patients to undergo advanced genetic testing.<\/p>\n<p>Helping guide treatment decisions<\/p>\n<p class=\"wp-block-paragraph\">For patients with meningiomas, recurrence risk can influence follow-up care, imaging frequency and whether radiation therapy should be considered. The study found that AI-based predictions remained useful even after accounting for traditional clinical factors such as tumor grade, the extent to which surgery was able to remove the tumor and patient age.<\/p>\n<p class=\"wp-block-paragraph\">Researchers also found that the AI models could identify patterns of tumor heterogeneity \u2014 differences within the same tumor \u2014 that may help explain why some tumors behave more aggressively or respond differently to treatment.<\/p>\n<p class=\"wp-block-paragraph\">The researchers note that additional prospective studies are needed before the AI models can be used routinely in clinical care. Still, they say the findings lay the groundwork for more accessible, personalized care for patients with meningiomas \u2014 and potentially for similar AI approaches in other cancers.<\/p>\n<p class=\"wp-block-paragraph\">&#8220;The aim is to make these algorithms readily and simply accessible for use globally, improving patient care across many healthcare settings,&#8221; says Dr. Zadeh.<\/p>\n<p class=\"wp-block-paragraph\">For a complete list of authors, disclosures and funding, review the <a href=\"https:\/\/www.thelancet.com\/journals\/landig\/article\/PIIS2589-7500(26)00009-9\/fulltext\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">publication<\/a>.<\/p>\n<p class=\"wp-block-paragraph\">###<\/p>\n<p class=\"wp-block-paragraph\">About Mayo Clinic <br \/><a href=\"https:\/\/www.mayoclinic.org\/about-mayo-clinic?mc_id=us&amp;utm_source=newsnetwork&amp;utm_medium=l&amp;utm_campaign=mayoclinic&amp;geo=national&amp;placementsite=enterprise&amp;invsrc=other&amp;cauid=100721\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Mayo Clinic<\/a> is a nonprofit organization committed to innovation in clinical practice, education and research, and providing compassion, expertise and answers to everyone who needs healing. Visit the <a href=\"https:\/\/newsnetwork.mayoclinic.org\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Mayo Clinic News Network<\/a> for additional Mayo Clinic news.<\/p>\n<p class=\"wp-block-paragraph\">About Mayo Clinic Platform <br \/>Founded on Mayo Clinic&#8217;s dedication to patient-centered care, <a href=\"https:\/\/www.mayoclinicplatform.org\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Mayo Clinic Platform<\/a> enables new knowledge, new solutions, and new technologies through collaborations with health technology innovators to create a healthier world. To learn more, visit Mayo Clinic Platform at <a href=\"https:\/\/www.mayoclinicplatform.org\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">www.mayoclinicplatform.org<\/a>.<\/p>\n<p class=\"wp-block-paragraph\">Media contact:<\/p>\n<p>Related Articles<\/p>\n","protected":false},"excerpt":{"rendered":"Neurosciences June 8, 2026 ROCHESTER, Minn. \u2014 Mayo Clinic researchers and collaborators have shown that artificial intelligence (AI)&hellip;\n","protected":false},"author":2,"featured_media":724351,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[64,63,137,500],"class_list":["post-724350","post","type-post","status-publish","format-standard","has-post-thumbnail","category-healthcare","tag-au","tag-australia","tag-health","tag-healthcare"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/724350","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/comments?post=724350"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/724350\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media\/724351"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media?parent=724350"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/categories?post=724350"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/tags?post=724350"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}