{"id":730190,"date":"2026-06-11T18:34:19","date_gmt":"2026-06-11T18:34:19","guid":{"rendered":"https:\/\/www.newsbeep.com\/au\/730190\/"},"modified":"2026-06-11T18:34:19","modified_gmt":"2026-06-11T18:34:19","slug":"new-system-for-flagging-retracted-papers-finds-scores-of-them-in-cochrane-reviews-retraction-watch","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/au\/730190\/","title":{"rendered":"New system for flagging retracted papers finds scores of them in Cochrane reviews \u2013 Retraction Watch"},"content":{"rendered":"<p><a href=\"https:\/\/retractionwatch.com\/wp-content\/uploads\/2021\/02\/1200px-Cochrane_logo_stacked.svg_.png\" rel=\"nofollow noopener\" target=\"_blank\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/www.newsbeep.com\/au\/wp-content\/uploads\/2026\/06\/1200px-Cochrane_logo_stacked.svg_-1024x1024.png\" alt=\"\" class=\"wp-image-121500\" style=\"width:250px\"  \/><\/a><\/p>\n<p class=\"wp-block-paragraph\">Cochrane has implemented a new system for checking whether any of its thousands of published reviews include retracted studies in their analyses, the organization announced today. The effort already has turned up dozens of reviews that do and will now get closer scrutiny to ensure their results and recommendations hold up.<\/p>\n<p class=\"wp-block-paragraph\">Cochrane publishes systematic reviews on health-related topics that evaluate the strength of evidence on particular treatments and interventions. Professional organizations and policymakers use the <a href=\"https:\/\/www.cochranelibrary.com\/cdsr\/reviews\" rel=\"nofollow noopener\" target=\"_blank\">more than 9,500 reviews<\/a> when developing recommendations. Recently a study of anesthesia clinical trials found a <a href=\"https:\/\/www.nature.com\/articles\/d41586-023-02299-w\" rel=\"nofollow noopener\" target=\"_blank\">high rate of the studies with faked or flawed data<\/a>, and another revealed that retracted studies included in systematic reviews \u2014 17% of which were Cochrane reviews \u2014 <a href=\"https:\/\/www.bmj.com\/content\/389\/bmj-2024-082068\" rel=\"nofollow noopener\" target=\"_blank\">had a large impact<\/a> on clinical guidelines derived from them.\u00a0<\/p>\n<p class=\"wp-block-paragraph\">Last year, Cochrane rolled out a feature in its database of reports of clinical trials, called CENTRAL, <a href=\"https:\/\/www.cochrane.org\/about-us\/news\/cochrane-launches-new-feature-identify-retracted-publications\" rel=\"nofollow noopener\" target=\"_blank\">to flag retracted studies<\/a>. The publisher pulls data on retracted papers from the Retraction Watch Database, <a href=\"https:\/\/www.crossref.org\/blog\/retraction-watch-retractions-now-in-the-crossref-api\/\" rel=\"nofollow noopener\" target=\"_blank\">via CrossRef<\/a>. Now, they have <a href=\"https:\/\/www.cochrane.org\/about-us\/news\/cochrane-strengthens-systems-manage-retracted-publications-its-published-reviews\" rel=\"nofollow noopener\" target=\"_blank\">extended the process<\/a> to routinely identify systematic reviews that rely on retracted papers.<\/p>\n<p class=\"wp-block-paragraph\">\u201cWhat we are looking at is studies that have been retracted that contribute results or findings to the conclusions of the Cochrane review,\u201d Ella Flemyng, Cochrane\u2019s head of editorial policy and research integrity, told Retraction Watch. \u201cSo if a study was already excluded, or it was just a general reference in the introduction or the discussion, we didn\u2019t want to prioritize those.\u201d<\/p>\n<p class=\"wp-block-paragraph\">The publisher has developed <a href=\"https:\/\/www.cochrane.org\/sites\/default\/files\/uploads\/PDFs\/Flowchart%20to%20determine%20significant%20impact%20of%20a%20study%20or%20studies.pdf\" rel=\"nofollow noopener\" target=\"_blank\">a workflow<\/a> for assessing the impact of the retracted work on the systematic review, also announced today alongside <a href=\"https:\/\/www.cochrane.org\/sites\/default\/files\/uploads\/PDFs\/Guidance%20document%20to%20accompany%20flowchart%20to%20determine%20significant%20impact%20of%20study%20or%20studies%20with%20an%20associated%20retraction%20on%20a%20Cochrane%20Review%20-%20Final%20(1).pdf\" rel=\"nofollow noopener\" target=\"_blank\">guidance<\/a> for implementing it.\u00a0<\/p>\n<p class=\"wp-block-paragraph\">\u201cCochrane has very rigorous methodological standards for developing systematic reviews in terms of identifying studies that have been retracted while you\u2019re developing the review itself,\u201d Flemyng said. \u201cThe gap that we had is when retractions happen after the publication of the systematic review. This new framework allows us to inform readers as quickly as we become aware of this impact on the evidence.\u201d<\/p>\n<p class=\"wp-block-paragraph\">Two published reviews served as test subjects while Cochrane developed that framework. One review, on the <a href=\"https:\/\/www.cochranelibrary.com\/cdsr\/doi\/10.1002\/14651858.CD007807.pub4\/full\" rel=\"nofollow noopener\" target=\"_blank\">effects of antioxidants on reduced fertility<\/a>, was flagged in December 2023 by the Feet of Clay Detector for containing four retracted papers. Cochrane placed an editorial note on the review a year later. In total, seven studies included in the review have been retracted since it was published, with another two studies marked with expressions of concern. Using Cochrane\u2019s new framework, the authors evaluated how each study contributed to the overall analysis and the effect it had on the assessment.<\/p>\n<p class=\"wp-block-paragraph\">\u201cIn the next update of this Cochrane review, these nine studies will be excluded from the analyses,\u201d the March 5 editorial note states. \u201cThe studies with retractions will be moved to the excluded studies table and the studies with expressions of concern will be moved to studies awaiting classification.\u201d<\/p>\n<p class=\"wp-block-paragraph\">Similarly, <a href=\"https:\/\/www.cochranelibrary.com\/cdsr\/doi\/10.1002\/14651858.CD002249.pub5\/full\" rel=\"nofollow noopener\" target=\"_blank\">a 2016 review<\/a> on antiestrogens for improving fertility in women with polycystic ovary syndrome \u2014 now called polyendocrine metabolic ovarian syndrome \u2014 included four studies that have since been retracted. Following the framework, the authors determined removing them would not change the overall findings of the review. A May 22 editorial note includes details about each of the retracted studies.<\/p>\n<p class=\"wp-block-paragraph\">\u201cIt\u2019s important that readers will know when reviews have been checked \u2014 and the protocol does that,\u201d said Jodi Schneider of the University of Wisconsin\u2013Madison, who studies the persistence of retracted papers in the published literature. \u201cPublishing an editorial notice indicating that the review has been checked, even if authors find minimal impact, is important.\u201d<\/p>\n<p class=\"wp-block-paragraph\">In checking all studies included in all systematic reviews, Cochrane found \u201cjust under 1%\u201d of its 9,500 published systematic reviews include retracted papers in their analyses, Flemyng said. Now that the publisher has developed and tested the new framework, the staff will begin notifying the authors of those reviews about the retracted studies and encouraging them to follow the framework to determine the impact on the review\u2019s recommendations.<\/p>\n<p class=\"wp-block-paragraph\">Cochrane will also start putting editorial notes on reviews as soon as they are flagged for including retracted papers. Once authors have completed a review as outlined in the new framework, Cochrane will update the editorial note.<\/p>\n<p class=\"wp-block-paragraph\">In the future, Cochrane hopes to automate more steps in the process, such as adding an editorial note on affected reviews and notify authors more quickly, Flemyng said.\u00a0<\/p>\n<p class=\"wp-block-paragraph\">Schneider, who called the new framework \u201cexcellent,\u201d suggested an area for future development could be to assess studies that have been flagged as problematic by <a href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2025.09.03.25334905v3\" rel=\"nofollow noopener\" target=\"_blank\">INSPECT-SR<\/a> or some other criteria but have not been retracted.\u00a0<\/p>\n<p class=\"wp-block-paragraph\">\u201cCochrane reviews inform guidelines, they inform clinical decisions, they inform health decisions. So we need to make sure that the underlying evidence remains reliable,\u201d Flemyng said. \u201cIf studies are being retracted, we need to make sure the systematic reviews that are based on that evidence are also updated so that we can continue to have relevant, up-to-date evidence informing health and care-related decisions and policies.\u201d<\/p>\n<p class=\"wp-block-paragraph\">Like Retraction Watch? You can make a\u00a0<a href=\"http:\/\/paypal.com\/us\/fundraiser\/charity\/1909130\" rel=\"nofollow noopener\" target=\"_blank\">tax-deductible contribution to support our work<\/a>, follow us\u00a0<a href=\"http:\/\/twitter.com\/RetractionWatch\" rel=\"nofollow noopener\" target=\"_blank\">on X<\/a> or <a href=\"https:\/\/bsky.app\/profile\/retractionwatch.com\" rel=\"nofollow noopener\" target=\"_blank\">Bluesky<\/a>, like us\u00a0<a href=\"https:\/\/www.facebook.com\/pages\/Retraction-Watch\/119209094864356\" rel=\"nofollow noopener\" target=\"_blank\">on Facebook<\/a>, follow us <a href=\"https:\/\/www.linkedin.com\/company\/retractionwatch\/\" rel=\"nofollow noopener\" target=\"_blank\">on LinkedIn<\/a>, add us to your\u00a0<a href=\"https:\/\/retractionwatch.com\/feed\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">RSS reader<\/a>, or subscribe to our\u00a0<a href=\"http:\/\/eepurl.com\/bNRlUn\" rel=\"nofollow noopener\" target=\"_blank\">daily digest<\/a>. If you find a retraction that\u2019s\u00a0<a href=\"http:\/\/retractiondatabase.org\/RetractionSearch.aspx\" rel=\"nofollow noopener\" target=\"_blank\">not in our database<\/a>, you can\u00a0<a href=\"https:\/\/docs.google.com\/forms\/d\/e\/1FAIpQLSeAsw4i5J8M7sOQ9GiG0_dglkim9gdPPba92yZRLfCq4u-o7w\/viewform?c=0&amp;w=1\" rel=\"nofollow noopener\" target=\"_blank\">let us know here<\/a>. For comments or feedback, email us at\u00a0<a href=\"https:\/\/retractionwatch.com\/cdn-cgi\/l\/email-protection\" class=\"__cf_email__\" data-cfemail=\"730716121e33011607011210071a1c1d041207101b5d101c1e\" rel=\"nofollow noopener\" target=\"_blank\">[email\u00a0protected]<\/a>.<\/p>\n<p>\n\tRelated\n<\/p>\n<p>\t<script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script><\/p>\n","protected":false},"excerpt":{"rendered":"Cochrane has implemented a new system for checking whether any of its thousands of published reviews include retracted&hellip;\n","protected":false},"author":2,"featured_media":730191,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[64,63,137,500],"class_list":["post-730190","post","type-post","status-publish","format-standard","has-post-thumbnail","category-healthcare","tag-au","tag-australia","tag-health","tag-healthcare"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/730190","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/comments?post=730190"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/730190\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media\/730191"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media?parent=730190"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/categories?post=730190"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/tags?post=730190"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}