{"id":929095,"date":"2026-10-15T13:34:22","date_gmt":"2026-10-15T13:34:22","guid":{"rendered":"https:\/\/www.newsbeep.com\/au\/929095\/"},"modified":"2026-10-15T13:34:22","modified_gmt":"2026-10-15T13:34:22","slug":"fda-approved-ketamine-fights-depression-better-than-decades-on-prozac-patients","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/au\/929095\/","title":{"rendered":"FDA-approved ketamine fights depression better than decades on Prozac: patients"},"content":{"rendered":"<p>Doctors at one Long Island hospital are using ketamine treatments to fight clinical depression \u2013 a medicine one patient says works better and faster than decades on Prozac.<\/p>\n<p>Patients suffering from severe depression at Mather Hospital are taking an esketamine nasal spray called Spravato, which 66-year-ld Ellen Talmage said has changed her life in a way other drugs could not.<\/p>\n<p>Some 62% of Mather\u2019s near-40 patients in the program report having seen improvements in symptoms.<\/p>\n<p>Patient Ellen Talmage, 66, receives FDA-regulated ketamine sprays for her depression at Mather Hospital in Port Jefferson, Long Island. Brigitte Stelzer for NY Post<\/p>\n<p>\u201cI\u2019m so much better that after this [interview], I\u2019m picking up my daughter-in-law and the two grandbabies, and we\u2019re going to the ocean,\u201d Talmage said.<\/p>\n<p>It\u2019s a far cry from how the once reclusive Baiting Hollow woman used to need anxiety medication just for a trip to the grocery store, where she would often break down crying.<\/p>\n<p>\u201cI booked tickets once to a really expensive concert for my birthday, and I couldn\u2019t go \u2013 that was just part of the deal\u2026 anybody who\u2019s had it for that long, you miss out on a lot of Christmases,\u201d she said.<\/p>\n<p>Doctors at the Northwell hospital believe the treatment could be a game changer for the future.<\/p>\n<p>Talmage has been on FDA-regulated ketamine sprays for her depression for about a year. Northwell<\/p>\n<p>\u201cFrom going to not being able to get out of bed and dress yourself to thinking about the future and having a job and having a purpose and meaning in life,\u201d Dr. Erin Dainer, Mather Hospital\u2019s psychiatry chair in Port Jefferson, told The Post.\u00a0<\/p>\n<p>\u201cI don\u2019t see that with other treatments the way I do with this.\u201d<\/p>\n<p>The multiweek program begins with a low dose of 56 milligrams, administered in person twice a week, and is gradually increased as patients respond.\u00a0<\/p>\n<p>Users are held for two hours after each session in comfortable chairs  with TV and music to be monitored for safety reasons, as the drug can cause some vivid reactions.<\/p>\n<p>Talmage likened it to riding Space Mountain.<\/p>\n<p>\u201cThat\u2019s the best way I can kind of describe it \u2013 because <a href=\"https:\/\/nypost.com\/2026\/02\/02\/us-news\/inside-the-li-facility-letting-patients-trip-on-drugs-drink-beer-and-gorge-on-potato-chips\/\" rel=\"nofollow noopener\" target=\"_blank\">it\u2019s definitely colors and whatever<\/a>,\u201d she said.<\/p>\n<p>While conventional antidepressants target the hormones serotonin and norepinephrine, the spray instead focuses on \u201ca completely different pathway\u201d \u2013 hitting NMDA (N-methyl-D-aspartate) receptors at the cellular level for mood altering.<\/p>\n<p>Mather inpatient psychiatrist Paniz Johari believes the FDA-approved esketamine will play a seismically shifting role in managing treatment-resistant depression treatment within the next decade.<\/p>\n<p>Dr. Erin Dainer, the chair of Psychiatry, and Dr. Paniz Johari, M.D. of psychiatry, at Mather Hospital in Port Jefferson on Aug. 1, 2026. Brigitte Stelzer for NY Post<\/p>\n<p>\u201cI think that\u2019s hard to say, but at the rate we\u2019re going, it\u2019s looking like that to me,\u201d she said.<\/p>\n<p>The Mather staff is also well aware of the stigma surrounding vastly different on-the-street ketamine or \u201cSpecial K,\u201d like that of which \u201cFriends\u201d star<a href=\"https:\/\/nypost.com\/2026\/06\/09\/us-news\/matthew-perry-doctor-claims-he-was-never-really-a-physician-so-should-be-let-out-of-prison\/\" rel=\"nofollow noopener\" target=\"_blank\"> Matthew Perry fatally overdosed<\/a>.<\/p>\n<p>\u201cMatthew Perry absolutely should never have happened,\u201d Dainer said.\u00a0<\/p>\n<p>The multiweek program begins with a low dose of 56 milligrams, administered in person twice a week, and is gradually increased as patients respond. Northwell<\/p>\n<p>\u201cThat\u2019s why we have so many regulations with this medication because we want to ensure safety; we want to ensure efficacy.\u201d<\/p>\n<p>\t\t\t\t\t\t\tStart your day with all you need to know\t\t\t\t\t\t<\/p>\n<p class=\"inline-module__cta\">\n\t\t\t\t\t\t\tMorning Report delivers the latest news, videos, photos and more.\t\t\t\t\t\t<\/p>\n<p>\t\t\t\t\t\tThanks for signing up!\n\t\t\t\t<\/p>\n<p>Another patient, who wished to remain anonymous, credited the treatments with giving him the courage to pursue becoming a peer-to-peer counselor to help others who are suffering.\u00a0<\/p>\n<p>\u201cI think it\u2019s a big thing between the ketamine and helping other people, that it gives you a purpose,\u201d he said.<\/p>\n","protected":false},"excerpt":{"rendered":"Doctors at one Long Island hospital are using ketamine treatments to fight clinical depression \u2013 a medicine one&hellip;\n","protected":false},"author":2,"featured_media":929096,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[64,63,4830,5607,137,44554,60014,373424,514,515,23741,176849,24019],"class_list":["post-929095","post","type-post","status-publish","format-standard","has-post-thumbnail","category-mental-health","tag-au","tag-australia","tag-depression","tag-exclusive","tag-health","tag-long-island","tag-matthew-perry","tag-medical-miracles","tag-mental-health","tag-mentalhealth","tag-metro","tag-northwell-health","tag-prescription-drugs"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/929095","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/comments?post=929095"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/929095\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media\/929096"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media?parent=929095"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/categories?post=929095"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/tags?post=929095"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}