{"id":952171,"date":"2026-11-04T10:10:09","date_gmt":"2026-11-04T10:10:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/au\/952171\/"},"modified":"2026-11-04T10:10:09","modified_gmt":"2026-11-04T10:10:09","slug":"australia-is-set-to-get-a-wegovy-pill-how-does-it-compare-with-weight-loss-injections","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/au\/952171\/","title":{"rendered":"Australia is set to get a Wegovy pill. How does it compare with weight-loss injections?"},"content":{"rendered":"<p>A new tablet version of <a href=\"https:\/\/www.wegovy.com\/\" rel=\"nofollow noopener\" target=\"_blank\">Wegovy<\/a>, a peptide used to help people lose weight, has been approved for the first time in Australia.<\/p>\n<p>Until now, the best-known medicines in this group (<a href=\"https:\/\/doi.org\/10.1056\/NEJMoa2032183\" rel=\"nofollow noopener\" target=\"_blank\">semaglutide<\/a>, sold as Wegovy or Ozempic, and tirzepatide, sold as Mounjaro), have generally required weekly injections. The <a href=\"https:\/\/www.abc.net.au\/news\/2026-11-03\/weight-loss-tablet-cleared-for-use-in-australia\/107343340\" rel=\"nofollow noopener\" target=\"_blank\">new daily tablet<\/a> offers another option for people who would prefer not to (or can\u2019t) inject themselves. <\/p>\n<p>But how does it work? And will swallowing a pill make weight loss easier, cheaper or safer?<\/p>\n<p>What are Wegovy pills, and what\u2019s changed?<\/p>\n<p>Wegovy contains semaglutide, a medicine that copies the action of a naturally occurring hormone called glucagon-like peptide-1 (GLP-1). This hormone helps regulate blood sugar, appetite and digestion.<\/p>\n<p>On Tuesday, Australia\u2019s <a href=\"https:\/\/www.tga.gov.au\/resources\/prescription-medicines-registrations\/wegovy-novo-nordisk-pharmaceuticals-pty-ltd\" rel=\"nofollow noopener\" target=\"_blank\">Therapeutic Goods Administration (TGA)<\/a> registered four strengths of <a href=\"https:\/\/www.tga.gov.au\/resources\/artg?keywords=wegovy+tablet\" rel=\"nofollow noopener\" target=\"_blank\">Wegovy tablets<\/a>: 1.5mg, 4mg, 9mg and 25mg. <\/p>\n<p>This makes it the first GLP-1 medicine approved in Australia in tablet form specifically for weight management.<\/p>\n<p>How do the tablets work, and who are they for?<\/p>\n<p>Semaglutide acts on the brain and digestive system. It reduces hunger, increases feelings of fullness and slows how quickly food leaves the stomach. This can help people feel satisfied with smaller meals and reduce how often they feel hungry.<\/p>\n<p>The medicine is intended for <a href=\"https:\/\/doi.org\/10.1038\/s41591-022-02026-4\" rel=\"nofollow noopener\" target=\"_blank\">adults living with obesity, or people who are overweight<\/a> and have other weight-related health conditions. It may also be prescribed to some people with <a href=\"https:\/\/doi.org\/10.1056\/NEJMoa2307563\" rel=\"nofollow noopener\" target=\"_blank\">heart (cardiovascular) disease<\/a> to reduce their risk of serious heart problems, such as heart attack or stroke.<\/p>\n<p>These medicines are <a href=\"https:\/\/doi.org\/10.64628\/AA.ax6u5kfrj\" rel=\"nofollow noopener\" target=\"_blank\">not intended as a quick fix<\/a> for people wanting to lose a few kilograms. They are prescription treatments that <a href=\"https:\/\/doi.org\/10.64628\/AA.9symaqs74\" rel=\"nofollow noopener\" target=\"_blank\">should be considered as part of a person\u2019s broader health needs<\/a>, with guidance from a health-care professional.<\/p>\n<p>How do the pills compare to injections?<\/p>\n<p>The Wegovy tablet must be taken <a href=\"https:\/\/www.wegovy.com\/obesity\/starting-wegovy\/starting-wegovy-pill.html\" rel=\"nofollow noopener\" target=\"_blank\">daily, on an empty stomach with a small amount of water<\/a>, with a <a href=\"https:\/\/www.novo-pi.com\/wegovy.pdf#guide\" rel=\"nofollow noopener\" target=\"_blank\">30-minute wait<\/a> before you eat or drink anything other than water. They contain a special absorption aid to pass through stomach acid, to allow it to be absorbed properly and work effectively.<\/p>\n<p>In contrast, the injection can be done any time of day, once weekly, with or without food. <\/p>\n<p>Both formats work to make you stay <a href=\"https:\/\/doi.org\/10.1056\/NEJMoa2500969\" rel=\"nofollow noopener\" target=\"_blank\">fuller faster, and trials showed similar gastrointestinal effects<\/a> especially when first starting.<\/p>\n<p>Overall, they show similar rates of weight loss, <a href=\"https:\/\/doi.org\/10.1056\/NEJMoa2500969\" rel=\"nofollow noopener\" target=\"_blank\">with the tablet showing a 14% body weight loss over 64\u201368 weeks<\/a>, and the injection <a href=\"https:\/\/doi.org\/10.1056\/nejmoa2032183\" rel=\"nofollow noopener\" target=\"_blank\">showing a 15% weight reduction<\/a>. However, the pill\u2019s effectiveness relies on people remembering to take it each day and not eat or drink within half an hour of the dose, rather than just remembering to inject the drug once a week.<\/p>\n<p>What are the risks?<\/p>\n<p>Common side effects \u2013 affecting around 80% of patients \u2013 include <a href=\"https:\/\/doi.org\/10.1016\/s0140-6736(23)01185-6\" rel=\"nofollow noopener\" target=\"_blank\">nausea, vomiting, diarrhoea, indigestion and constipation<\/a>. <\/p>\n<p>Less common, but more serious side effects include <a href=\"https:\/\/doi.org\/10.3389\/fendo.2021.645563\" rel=\"nofollow noopener\" target=\"_blank\">kidney injury, pancreatitis and gallbladder problems<\/a>. <\/p>\n<p>Higher doses <a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(23)01127-3\" rel=\"nofollow noopener\" target=\"_blank\">make negative side effects<\/a> more severe. With a tablet, it\u2019s important for people to know that, just as for an injection, doubling up their dose won\u2019t encourage faster results and could cause harm.<\/p>\n<p><a href=\"https:\/\/doi.org\/10.1016\/j.obpill.2025.100172\" rel=\"nofollow noopener\" target=\"_blank\">Doctor appointments are short<\/a>, meaning they sometimes lack proper screening for eating disorders, body image or other psychological issues. Previous research has also highlighted <a href=\"https:\/\/doi.org\/10.1001\/jamanetworkopen.2024.23385\" rel=\"nofollow noopener\" target=\"_blank\">a link between suicidal thoughts and GLP-1 use<\/a>. So unless these issues are discussed in appointments, it could lead to negative outcomes for patients.<\/p>\n<p>An oral tablet may be easier for people who don\u2019t like needles or <a href=\"https:\/\/www.livescience.com\/health\/heart-circulation\/why-are-some-peoples-veins-hard-to-find\" rel=\"nofollow noopener\" target=\"_blank\">have trouble using them<\/a>, and could reduce potential injection-related injuries. Recently, needle and syringe programs have been <a href=\"https:\/\/www.abc.net.au\/news\/2026-08-06\/peptide-increase-impacting-needle-exchange-facilities\/106965078\" rel=\"nofollow noopener\" target=\"_blank\">overwhelmed with demand for needles used for GLP-1s and other peptides<\/a>.<\/p>\n<p>When will pills be available, and what will they cost?<\/p>\n<p>The TGA approval doesn\u2019t mean you can walk into your doctor and get a script today. <\/p>\n<p>Before Wegovy tablets hit THE shelves, the TGA will complete a final review of packaging and production, as well as retail pricing. Novo Nordisk, the company that manufactures Wegovy, aims to have tablets available in Australia <a href=\"https:\/\/www.theguardian.com\/science\/2026\/nov\/04\/australias-first-glp-1-weight-loss-pill-has-been-approved-how-much-will-it-cost-and-where-it-will-it-be-available\" rel=\"nofollow noopener\" target=\"_blank\">by the end of the year<\/a>. <\/p>\n<p>It is also important to distinguish TGA approval from Pharmaceutical Benefits Scheme (PBS) listing. <a href=\"https:\/\/www.tga.gov.au\/sites\/default\/files\/2024-09\/auspar-wegovy-01-240904-pi.pdf\" rel=\"nofollow noopener\" target=\"_blank\">TGA approval means<\/a> a medicine can be prescribed for its approved uses. PBS listing means the government subsidises its cost. Wegovy is <a href=\"https:\/\/theconversation.com\/would-subsidising-weight-loss-drugs-make-health-care-fairer-292687\" rel=\"nofollow noopener\" target=\"_blank\">not currently subsidised<\/a> through the PBS for weight management, meaning patients should expect to pay the full price.<\/p>\n<p>Official pricing <a href=\"https:\/\/www.abc.net.au\/news\/2026-11-03\/weight-loss-tablet-cleared-for-use-in-australia\/107343340\" rel=\"nofollow noopener\" target=\"_blank\">hasn\u2019t been released yet<\/a>. However, the <a href=\"https:\/\/www.mediremind.com.au\/wegovy-cost-australia-2026\" rel=\"nofollow noopener\" target=\"_blank\">weekly injection costs A$250\u2013$450<\/a> a month and the pill\u2019s out-of-pocket costs are likely to be similar.<\/p>\n<p>Is this a \u2018magic pill\u2019?<\/p>\n<p>This pill isn\u2019t meant to be used by itself. The TGA <a href=\"https:\/\/www.tga.gov.au\/resources\/prescription-medicines-registrations\/wegovy-novo-nordisk-pharmaceuticals-pty-ltd\" rel=\"nofollow noopener\" target=\"_blank\">has approved Wegovy tablets<\/a> to use alongside a reduced-calorie diet and increased physical activity.<\/p>\n<p>It\u2019s also important to follow prescriber guidelines, <a href=\"https:\/\/doi.org\/10.1002\/oby.24336\" rel=\"nofollow noopener\" target=\"_blank\">eat nutritious food<\/a>, and do weight training to help avoid muscle loss. <\/p>\n<p>This is why \u201c<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/hpja.284\" rel=\"nofollow noopener\" target=\"_blank\">lifestyle prescribing<\/a>\u201d should accompany any weight-loss drugs, which means GPs should also make a clear plan with patients to encourage healthy eating and regular exercise, alongside weight-loss medications.<\/p>\n<p>This matters because when people lose weight quickly, some of what they lose is lean muscle, not just body fat. <\/p>\n<p>Secondly, the weight can come back if you stop taking Wegovy without having changed your lifestyle. <a href=\"https:\/\/doi.org\/10.1111\/dom.14725\" rel=\"nofollow noopener\" target=\"_blank\">Follow-up research<\/a> with participants <a href=\"https:\/\/doi.org\/10.1016\/j.eclinm.2026.103796\" rel=\"nofollow noopener\" target=\"_blank\">has found<\/a> people regained about two-thirds of the weight they had lost within a year of stopping these medications.<\/p>\n","protected":false},"excerpt":{"rendered":"A new tablet version of Wegovy, a peptide used to help people lose weight, has been approved for&hellip;\n","protected":false},"author":2,"featured_media":952172,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[33],"tags":[64,63,137,490],"class_list":["post-952171","post","type-post","status-publish","format-standard","has-post-thumbnail","category-medication","tag-au","tag-australia","tag-health","tag-medication"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/952171","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/comments?post=952171"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/posts\/952171\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media\/952172"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/media?parent=952171"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/categories?post=952171"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/au\/wp-json\/wp\/v2\/tags?post=952171"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}