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The Baltimore Orioles and Jackson Holliday take the field against George Springer and the Toronto Blue Jays on Sunday, in the final game of a three-game series at Rogers Centre. Oddsmakers list the Blue Jays as -192 moneyline favorites, while giving the underdog Orioles +157 moneyline odds to win. Toronto is a 1.5-run favorite (at +109 odds). An 8-run over/under is set in the game.

Here is everything you need to know from a betting perspective on the Blue Jays-Orioles game, regarding the run line, moneyline and total, plus expert picks.

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Blue Jays vs. Orioles Game Information & OddsWhen: Sunday, September 14, 2025 at 1:37 p.m. ETWhere: Rogers Centre in Toronto, OntarioHow to watch on TV: SNET and MASN2 Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Blue Jays -192 +157 8 -116 -104 -1.5 +109 -131 Blue Jays vs. Orioles PredictionScore Prediction: Blue Jays 6, Orioles 4Total Prediction: Over 8 runsWin Probabilities: Blue Jays 56%, Orioles 44%Blue Jays vs. Orioles Betting InsightsThe Blue Jays have entered the game as favorites 74 times this season and won 44, or 59.5%, of those games.Toronto has a record of 7-3 in games when oddsmakers favor them by at least -192 on the moneyline.Bookmakers have implied with the moneyline set for this matchup that the Blue Jays have a 65.8% chance to win.The Orioles have been victorious in 38, or 45.8%, of the 83 contests they have been chosen as underdogs in this season.This season, Baltimore has come away with a win three times in nine chances when named as an underdog of at least +157 or longer on the moneyline.The moneyline set for this matchup implies the Orioles have a 38.9% chance of coming away with a victory in the contest.Blue Jays Recent Betting PerformanceThe Blue Jays were the moneyline favorite for seven of their last 10 games, and they went 6-1 in those matchups.In their last 10 matchups (all 10 of them had set totals), the Blue Jays and their opponents combined to hit the over three times.The Blue Jays have gone 6-4-0 against the spread over their past 10 games.Blue Jays Recent Stats Stat Avg/Total Record 7-3 Runs Per Game 5.9 HR 13 ERA 3.03 K/9 8.7 Blue Jays Player InsightsVladimir Guerrero Jr. is hitting .305 with 33 doubles, 23 home runs and 79 walks.Guerrero’s home runs place him 51st in the majors, and he ranks 33rd in RBI.Guerrero has collected a hit in three games in a row. In his last five games he is hitting .421 with three walks and an RBI.Springer has hit 28 home runs to pace his team.Springer ranks 22nd in home runs in MLB, and 57th in RBI.Springer has three games in a row with at least one hit. In his last five games he is hitting .263 with a home run, three walks and an RBI.Ernie Clement is batting .277 with 29 doubles, two triples, nine home runs and 24 walks.Clement will look to build on his two-game hitting in this game. In his last five games he is batting .333 with a double, a walk and an RBI.Alejandro Kirk is batting .287 with 17 doubles, 12 home runs and 45 walks.Orioles Recent Betting PerformanceIn eight games as underdogs over the last 10 matchups, the Orioles have a record of 5-3.When it comes to hitting the over, the Orioles and their opponents are 2-7-1 in their last 10 games with a total.The Orioles have six wins against the spread in their last 10 chances.Orioles Recent Stats Stat Avg/Total Record 7-3 Runs Per Game 3.4 HR 9 ERA 2.86 K/9 7.9 Orioles Player InsightsGunnar Henderson paces the Orioles with 62 runs batted in while racking up a team-high batting average of .270.Among all hitters in MLB, Henderson ranks 112th in homers and 97th in RBI.Holliday’s 17 home runs lead his team.Holliday is 100th in home runs and 127th in RBI among all MLB hitters this year.Ryan Mountcastle is batting .256 with 18 doubles, five home runs and 14 walks.Colton Cowser is hitting .201 with 12 doubles, 13 home runs and 22 walks.Blue Jays vs. Yankees Highlights | MLB on FOX Blue Jays vs. Yankees Highlights | MLB on FOX

Check out the best highlights between the Toronto Blue Jays and the New York Yankees.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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