The Buffalo Bills are off to a 2-0 start in the 2025 season, knocking off the New York Jets in Week 2 in a blowout.
Now, they’ll take on another winless AFC East team, as the Miami Dolphins come to town on Thursday Night Football in Week 3. Miami is coming off a loss to the New England Patriots – 33-27 – after giving up three scores to Drake Maye.
Miami has allowed 33 points in both games so far this season, and now it has to face one of the most explosive offenses in the NFL led by reigning league MVP Josh Allen.
The Bills are obviously favorites at home in Week 3, and they’re looking to run the table against division opponents for as long as possible to capture another AFC East title.
Can Miami at least cover despite two poor showings to open 2025?
Here’s a breakdown of the odds, a player to watch and my prediction for this Thursday Night Football matchup.
Odds via DraftKings Sportsbook
Spread
Moneyline
Total
Dolphins Injury ReportBills Injury ReportJosh Allen, Quarterback, Buffalo Bills
This is a dream matchup for Allen, as Miami has allowed massive games to Daniel Jones and Drake Maye to open the season:
Allen only needed to throw for 148 yards to beat the Jets in Week 2, but he did throw for 394 yards and a pair of scores in Week 1. He should have a field day against a Miami secondary that has seen a ton of turnover since last season and has already been banged up in 2025.
The Dolphins have allowed 33 points in both of their games this season.
There’s just no way that I can bet on the Dolphins right now.
This team has allowed over 30 points to two average offenses, and now it has to face a Buffalo team that could end up being the highest-scoring team in the league in the 2025 season.
Buffalo has only lost three games at home since the start of the 2022 season, and it’s already shown that it can play a shoutout and win like it did in Week 1 against the Ravens.
Miami is 0-2 against the spread, failing to cover as a slight road underdog in Week 1 and a home favorite in Week 2. Mike McDaniel’s team appears to be going nowhere fast, as the defense is extremely leaky in the secondary after moving from Jalen Ramsey, Jevon Holland and Jordan Poyer in the offseason.
Buffalo’s defense didn’t look great in Week 1, but it held the Jets to just 10 points in Week 2 and controlled the game from the jump.
Even though Miami’s offense was more explosive against New England, it only scored 20 points on offense (one touchdown came from a punt return).
I think Buffalo – which was able to rest Allen at the end of the Week 2 win – wins in a blowout in a short week.
Pick: Bills -12.5 (-110 at DraftKings)
Odds refresh periodically and are subject to change.
If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.
Claim the latest DraftKings promo code offer today. Sign up and place a $5 bet to earn a guaranteed $200 in bonus bets plus over $200 off NFL Sunday Ticket. Regardless of the outcome of your wager,DraftKings will add eight $25 bonus bet tokens to your new account and award one promo code for a discounted NFL Sunday ticket subscription.