Global stocks extended their slide into a fourth day as concerns over lofty valuations and mixed signals from Federal Reserve officials on interest rates sapped investor sentiment.
The MSCI All Country World Index declined 0.1% in the longest losing streak in a month. Asian shares fell 0.8%, the most in September, with drug companies slumping after President Donald Trump announced a 100% levy on branded or patented pharmaceutical products. S&P 500 futures were little changed while Nasdaq 100 futures dropped 0.1%. Contracts for Europe rose 0.4%.