Big storylines from the early gamespublished at 00:35 BST
00:35 BST
NFL Sunday on BBC Sport
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These are the key storylines from the seven 18:00 BST games:
Eagles win battle of unbeaten teams
The Philadelphia Eagles and Tampa Bay Buccaneers came into this game unbeaten and the Eagles came out on top in a thriller.
They dominated early on, leading 24-6 at one point, but the Bucs fought back, the Eagles held on and it finished 31-25.
Dart leads Giants to debut win but Nabers injured
Quarterback Jaxson Dart impressed on his first start as the New York Giants pulled off one of the shocks of the season so far, beating Justin Herbert’s Los Angeles Chargers 21-18.
However, there wasn bad news for New York as star receiver Malik Nabers suffered a reported ACL injury.
Lions offence > Browns defence
The Detroit Lions’ explosive offence ws on top against the Cleveland Browns’ number one-ranked defence with Jahmyr Gibbs and Amon-Ra St. Brown impressing in a 34-10 win.
Bills hold off Saints to go 4-0
And the Buffalo Bills were expecting to easily beat the New Orleans Saints but were made to work hard to win 31-19 and remain unbeaten.