The stage is set for the 2025 NFL London Game with the Minnesota Vikings and Cleveland Browns prepared to lock horns in a Week 5 NFL battle. Carson Wentz and the Vikings fell to 2-2 on the season after coming up short against Aaron Rodgers and the Pittsburgh Steelers 24-21 in Dublin, Ireland. Meanwhile, the Browns, who are turning to rookie quarterback Dillon Gabriel as the starter, are sitting at 1-3 following a 34-10 Week 4 loss to the Detroit Lions.

Kickoff from Tottenham Hotspur Stadium is set for 9:30 a.m. ET on the NFL Network. Minnesota is a 3.5-point favorite in the latest Vikings vs. Browns odds, and the over/under for total points scored is 36. Minnesota is at -194 on the money line (risk $194 to win $100). Before making any Browns vs. Vikings picks, be sure to see what the SportsLine projection model has to say. 

New users can also target the DraftKings promo code, which offers $200 in bonus bets instantly if your bet wins:

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a sizzling 39-20 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.  

Now, the model has zeroed in on Browns vs. Vikings. You can head to SportsLine now to see its picks. Here are several NFL odds and betting lines for Vikings vs. Browns in London:

Vikings vs. Browns spread

Vikings -3.5 at DraftKings Sportsbook

Vikings vs. Browns over/under

36.5 points

Vikings vs. Browns money line 

Minnesota -194, Cleveland +160

Vikings vs. Browns picks

See picks at SportsLine

Vikings vs. Browns streaming 

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Why the Vikings can cover

Minnesota is 2-2-0 ATS following the Week 4 loss to Pittsburgh but still 4-1-0 ATS in international play. Wentz, who continues to start in place of an injured J.J. McCarthy, has thrown for 676 yards with four touchdowns in four career games against the Browns, and he has a plethora of weapons at his disposal including Justin Jefferson, Jordan Addison and T.J. Hockenson. The Vikings defense — which has a particularly good pass rush — will be putting plenty of pressure on rookie Dillon Gabriel, who will be making his first NFL start. See which team to back at SportsLine. 

Why the Browns can cover

Regardless of their record and going 2-2-0 ATS through Week 4, the Browns continue to have one of the best defenses in the NFL. The defense leads the league with fewest yards per game allowed (222.5) and rushing yards per game allowed (70.3). Cleveland’s pass rush ranks fourth overall with 152.3 yards allowed by air and has held Jefferson to under 100 yards. It has also forced Wentz into throwing five interceptions over his career, and they will pressure to trip him up again after he was picked off twice by Pittsburgh. See which team to back at SportsLine. 

New users can also check out the latest FanDuel promo code and get $300 in bonus bets instantly at FanDuel if your $5 bet wins. 

How to make Browns vs. Vikings picks

For the NFL London Game in Week 5, the model is leaning over the total, and also says one side of the spread hits in more than 50% of simulations. See what it is at SportsLine.

Who wins Vikings vs. Browns, and which side of the spread hits more than 50% of the time? Visit SportsLine now to see which side of the Browns vs. Vikings spread you need to jump, all from the model that is 39-20 on top-rated picks since 2024, and find out.