Oct 16, 2025, 07:28 PM ET
Anthony Santander‘s postseason for the Toronto Blue Jays ended Thursday, with Major League Baseball approving a roster substitution for the ailing outfielder.
Santander has been battling a back injury that led him to being scratched from Game 2 of the AL Championship Series against the Seattle Mariners. He started in right field in Game 3, but was replaced after two at-bats in an eventual 13-4 Toronto road win that cut its series deficit to 2-1.
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MLB’s announcement came a little over an hour before Game 4 on Thursday night in Seattle.
The league said Dr. Gary Green, its medical director, confirmed Santander’s injury “after a full review of the medical information.” He was replaced by Joey Loperfido on Toronto’s roster.
By rule, Santander can’t return for the Mariners series or for the subsequent series if the Blue Jays advance, meaning he’s ineligible to play in the World Series.
Santander signed a $92.5 million, five-year contract with Toronto last offseason but missed almost four months because of a left shoulder injury. He hit .175 with six home runs and 18 RBIs in 54 games.
He was hitting .200 (3 for 15) with no homers, 2 RBIs and 5 strikeouts in five games this postseason.