After the 49ers upset the Rams earlier in the season, Sean McVay claimed victory this time around in his coaching rivalry with his friend, Kyle Shanahan, thanks to Matthew Stafford. 

The Rams’ quarterback had a stellar performance on Sunday, throwing for 280 yards and four touchdowns in their 42-26 win over the 49ers. His second touchdown pass of the day gave him 400 passing touchdowns in his career, making Stafford just the ninth quarterback in NFL history to reach that threshold. 

Los Angeles improved to 7-2 on the season with the win, keeping pace with the Seattle Seahawks in the NFC West race ahead of next week’s major tilt. As for San Francisco, it dropped to 6-4 on the year, putting it behind in the NFC West race.

Here are the highlights from “America’s Game of the Week.” 

7:22p ET

George Kittle at least gives the 49ers’ faithful a highlight play

7:17p ET

Stafford with the no-look pass for his fourth TD of the day

7:13p ET

Rams come up with a big pick

6:49p ET

Rams respond again to a 49ers TD

6:46p ET

49ers continuing to hang around

6:37p ET

Matthew Stafford giving the Rams some cushion

6:33p ET

49ers find the end zone again and are making it interesting

5:57p ET

Rams carry 21-7 lead into halftime

5:47p ET

49ers finally find the end zone

5:40p ET

Rams force the turnover on downs

5:21p ET

Matthew Stafford is now Mr. 400

5:10p ET

Landman forces a fumble with a ‘Muhammad Ali punch’

4:56p ET

There goes Puka!

4:42p ET

Rams score on game’s first drive

Live Coverage for this began on 7:28p ET