The body protects itself from free radicals through the powerful antioxidants beta-carotene, flavonoids and tannins, which are present in persimmons. These compounds decrease oxidative stress, which contributes to aging, heart disease and cancer development. Research indicates that persimmon extracts demonstrate anti-inflammatory properties, by reducing inflammation markers, and protect cells from damage, according to animal model studies.

The fruit contains better free radical scavenging properties than several well-known fruits, because of its carotenoid and polyphenol content. The action helps prevent the progression of chronic diseases, which result in artery hardening. Research studies which used human participants to test persimmon supplements, demonstrated that people who consumed persimmon supplements each day, experienced increased blood antioxidant levels. The daily serving amount of this product provides automatic cell defense through natural body functions, without needing any extra medical treatment.