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Good morning. A new startup focused on GLP-1 drugs launched today, but unlike the dozens of other GLP-1 companies, this one isn’t studying weight loss.

The need-to-know this morning

Roche plans to launch Phase 3 studies of its leading obesity candidate this quarter after reporting that the drug led to significant weight loss in a mid-stage trial. 

Intellia Therapeutics said the FDA lifted a clinical hold on a Phase 3 study of its CRISPR gene-editing therapy for a condition called transthyretin amyloidosis, or ATTR, that mostly affects nerves. A clinical hold on a separate Phase 3 study of the therapy in ATTR that affects the heart remains in place.

New startup to develop a GLP-1 drug for addiction

A company called Baseline Therapeutics launched today with a focus on studying a GLP-1 drug for various substance use disorders.

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