According to cardiovascular research, inactivity sets off several biologic changes. The heart undergoes deconditioning, losing stroke volume and aerobic capacity, which makes routine exertion harder. Blood vessels also suffer, as lack of movement impairs endothelial function and promotes plaque build-up. Studies further show that reduced activity worsens metabolism, leading to weight gain, insulin resistance, and lipid disturbances, all of which fuel atherosclerosis. Scientists have also linked sedentary behaviour with chronic low-grade inflammation and less favourable heart-rate variability. Together, these pathways explain why staying active is consistently recommended by global health authorities.
