Former interim lightweight champion Dustin Poirier will cap his storied career Saturday with a trilogy fight against former featherweight champion Max Holloway in the main event of UFC 318. The main card is set for 10 p.m. ET from the Smoothie Center in New Orleans.

Holloway is a -142 favorite (risk $142 to win $100), while Poirier is priced at +120 (risk $100 to win $120) in the latest MMA odds for UFC 318: Holloway vs. Poirier 3, with Holloway favored to win via decision (+140).

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Before making any UFC 318 picks, make sure you see the MMA predictions and betting advice from SportsLine expert Daniel Vithlani. 

Vithlani is a highly analytical UFC bettor who has been a consistent winner for SportsLine members since making his debut in January 2023 with a 5-0 record for UFC 283. In fact, he’s up over $1,500 on his UFC main card picks!

His other highlights include calling an upset for Sean O’Malley (+210) against Aljamain Sterling (-250) at UFC 292 as part of a 4-1 main card, and his UFC 299 winners included underdog selections on Dustin Poirier (+190) against Benoit Saint Denis (-230) and Michael Page (+110) against Kevin Holland (-130). Anyone who has followed him could be way up.

This week at UFC 318: Holloway vs. Poirier 3, we can tell you Vithlani is backing Francisco Prado (-142) to get past Nikolay Veretennikov (+120) in a welterweight matchup on the preliminary card. 

He’s also backing a fighter who who “is a highly skilled kickboxer who can throw a diverse array of looks at his opponents” to pull off a MASSIVE VICTORY! You ABSOLUTELY need to see his UFC Fight Night picks before making any of your own!

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