Kansas City Chiefs quarterback Patrick Mahomes is already in the discussion as one of the greatest quarterbacks in NFL history, and he’s long been a top option in Fantasy football. However, he didn’t live up to his Fantasy football ADP in a down 2024 season, throwing for just 3,928 yards and 26 touchdowns — both career lows in his seven seasons as a full-time starter. Mahomes finished as the QB11 in CBS Sports Fantasy leagues last year and barely cracked the top 10 in 2023.

Now, Fantasy managers are beginning to question whether Mahomes’ peak years are behind him and if Kansas City’s offensive approach under head coach Andy Reid is evolving. That’s why having accurate, real-time 2025 Fantasy football positional rankings is crucial when preparing for your draft. Where should Mahomes land in your 2025 Fantasy football quarterback rankings? Before crafting your 2025 Fantasy football draft strategy, be sure to check out the 2025 Fantasy football positional rankings and cheat sheets from the proven computer model at SportsLine.

Last year, the model accurately predicted that Dolphins running back Raheem Mostert’s disappointing follow-up to a breakout 2023 season. It also called C.J. Stroud’s down year, predicted Jayden Daniels’ breakout campaign and projected James Cook to become one of Fantasy football’s elite running backs in 2024.

The same model has a proven track record providing Fantasy football tips, identifying A.J. Brown as a sleeper in 2020, nailing Jonathan Taylor’s monstrous season in 2021 and correctly predicting C.J. Stroud would take a step back in 2024. Additionally, it’s called past Fantasy football sleepers like Derrick Henry in 2019, Christian McCaffrey and Alvin Kamara in 2018 and Davante Adams in 2017. 

Now, SportsLine has simulated the entire NFL season 10,000 times and released its latest Fantasy football positional rankings 2025, along with plenty of sleepers, breakouts and busts at every position. Head to SportsLine now to see them. 

Top 2025 Fantasy football QB rankings

Here’s a look at SportsLine’s top 2025 Fantasy football QB picks: 

1. Lamar Jackson, Baltimore Ravens: Jackson had a career year in 2024, throwing for 4,172 yards and 41 touchdowns while averaging an impressive 8.8 yards per attempt and posting a 119.3 QB rating. On the ground, he added 915 rushing yards and four rushing touchdowns. His exceptional dual-threat abilities led him to finish more than 50 points ahead of any other quarterback in CBS Sports PPR leagues. Jackson’s continued development as a passer combined with his elite running skill firmly establishes him as the top fantasy QB entering 2025.

2. Josh Allen, Buffalo Bills: Though Jackson posted flashier stats, Allen earned the 2024 NFL MVP honors with 40 total touchdowns and over 4,000 yards of offense. He has ranked as a top-two fantasy quarterback for five consecutive seasons, proving his consistent value. Allen’s arm talent ranks among the best in NFL history, and his running ability often goes underappreciated.

3. Joe Burrow, Cincinnati Bengals: Burrow dominated the league last season, leading in completions (450), attempts (652), passing yards (4,918), and touchdowns (43). His chemistry with a strong receiving corps — Ja’Marr Chase, Tee Higgins, Chase Brown, and Mike Gesicki — sets the stage for another prolific season. Burrow remains a high-volume, high-scoring fantasy option heading into 2025. See more top QBs here.

Top 2025 Fantasy football RB rankings

Here’s a look at SportsLine’s top 2025 Fantasy football RB picks: 

1. Jahmyr Gibbs, Detroit Lions: David Montgomery and Gibbs have a thunder-and-lightning situation going in Detroit and there’s been more than enough work to go around. Gibbs led the NFL with 25 breakaway runs (carries of 15 yards or more) last season and he’s also a sensational receiver, catching 52 passes for 517 yards and four touchdowns. Montgomery’s presence is more complimentary than detrimental at this point and that’s why Gibbs is our top-ranked runner for 2025.

2. Bijan Robinson, Atlanta Falcons: Robinson isn’t quite as explosive as Gibbs, but he’s got the proverbial wiggle that you love to see in a running back. He evaded 83 tackles last season, the third-most among NFL running backs, and the Falcons piled him up with 365 touches. He’s a true workhorse running back in a league that has continued to shift towards spreading the wealth.

3. Saquon Barkley, Philadelphia Eagles: Barkley became the ninth running back in NFL history to rush for 2,000 yards last season, proving to be an ideal fit in Philadelphia. He had a chance to break the NFL rushing record in Week 17 but the Eagles opted to rest him for the postseason, which proved to be a prudent move. He’s such an enormous value to the team that it almost hurts his stock a little, because Philadelphia should be around come playoff time and will want him at his peak. He’s still a clearly viable option in the first round though. See more top RBs here.

Top 2025 Fantasy football WR rankings

Here’s a look at SportsLine’s top 2025 Fantasy football WR picks: 

1. Ja’Marr Chase, Cincinnati Bengals: Chase has been a dominant force since being taken with the fifth pick in the first round of the 2021 NFL Draft. He has surpassed 1,000 yards receiving in each of his first four seasons, including a career high in 2024. Last season, Chase finished with 127 receptions for 1,708 yards and 17 touchdowns. He also carried three times for 32 yards (10.7 average).

2. Malik Nabers, New York Giants: Although he caught passes from Daniel Jones, Tommy DeVito and Drew Lock, Nabers was fifth in catches (109) and seventh in receiving yards (1,204) with seven scores last year. He went over 100 yards in three outings, and with better QB play expected, Nabers is in line for another big season in 2025.

3. CeeDee Lamb, Dallas Cowboys: Lamb has been a consistent Fantasy football points leader in each of the last three seasons. The former first-round pick in the 2020 NFL Draft, he has 100 or more receptions over that stretch. In just 15 games last season, Lamb caught 101 passes for 1,194 yards and six touchdowns. In 2023, he had 135 receptions for 1,749 yards and 12 touchdowns. See more top WRs here.

Top 2025 Fantasy football TE rankings

Here’s a look at SportsLine’s top 2025 Fantasy football TE picks:

1. George Kittle, San Francisco 49ers: In 2024, Kittle had his best season for Fantasy managers since 2018, averaging 15.8 PPR points per game. Kittle has scored at least seven touchdowns in each of his past four seasons, and he saw his targets spike to 6.3 per game a season ago. The veteran tight end is coming off back-to-back 1,000-yard seasons, a big reason why SportsLine’s model ranks him as the No. 1 TE heading into 2025. 

2. Brock Bowers, Las Vegas Raiders: As a rookie, Bowers averaged nine targets per game. That high volume helped Bowers average 15.5 PPR points per game. He ended his incredible 2024 campaign with the most receptions by a rookie in NFL history (112) and the most yardage (1,194) by a rookie tight end in league history. Geno Smith marks a significant upgrade at quarterback in Las Vegas, so there’s no ceiling to what Bowers can do in 2025.

3. Trey McBride, Arizona Cardinals: McBride has cemented his status as a top-tier Fantasy tight end after a breakout 2024. McBride averaged 9.2 targets per game to lead all tight ends, catching 76% of his targets. He has only seven career touchdowns in 49 games, but SportsLine’s model expects he’ll be a differentiator at tight end to give your Fantasy squad an advantage every week. See more top TEs here.

Top 2025 Fantasy football defense rankings 

Here’s a look at SportsLine’s top three 2025 Fantasy football D/ST picks:

1. Philadelphia Eagles D/ST: Howie Roseman is one of the NFL’s best executives but his turnaround of the Philadelphia pass defense from 2023 to 2024 was masterful. They went from ranking 30th in points allowed and 26th in yards allowed to ranking second in scoring defense and first in total defense in just one offseason. Now most of the key pieces from that unit return.

2. Baltimore Ravens D/ST: Baltimore had the best run defense in football last season and should have an improved secondary after drafting Malaki Starks in the first round and signing Jaire Alexander. They’ve got high-level playmakers at every level in Kyle Van Noy, Roquan Smith and Kyle Hamilton.

3. Minnesota Vikings D/ST: They were the No. 5 scoring defense in the NFL last season and they led the NFL with 33 takeaways. Minnesota also scored three defensive touchdowns, and even if the takeaway numbers can’t be relied on, the boom potential here is too high to ignore. See more top D/ST here. 

Top 2025 Fantasy football kicker rankings

Here’s a look at SportsLine’s top 2025 Fantasy football K picks: 

1. Brandon Aubrey, Dallas Cowboys: Aubrey has the biggest leg in the league and he tied for second in the NFL in points (150) last season. He’s 76-of-85 on field goals the last two seasons and he’s a staggering 24-of-27 from 50 yards or more.

2. Matt Gay, Washington Commanders: Jayden Daniels is the rising tide that lifts all boats and this offense looks primed to be even better in 2025 after the offseason additions of Laremy Tunsil and Deebo Samuel. Gay was perfect from inside of 50 yards last season and closed the year strong, with 24 points in the final two games of the regular season.

3. Tyler Bass, Buffalo Bills: Despite only making 82.8% of his field goal attempts, Bass finished tied for ninth in scoring (131 points). He was perfect on field goals of more than 50 yards and also locked in during the 2025 NFL playoffs, going 6-for-6 overall.

How to find proven 2025 Fantasy football rankings

SportsLine has ranked almost every Fantasy-relevant player at every position and you can see their entire 2025 Fantasy football positional rankings now. You can only see their top sleepers, breakouts and busts at every position at SportsLine.

So who are the top players at every position and who is being underrated? Visit SportsLine now to get 2025 Fantasy Football cheat sheets for every single position, all from the model that regularly outperforms human rankings.