Data Skrive
Nick Pivetta takes the mound for the San Diego Padres on Friday against Mickey Moniak and the Colorado Rockies. First pitch is at 8:40 p.m. ET for this first game in a three-game series. The Padres are the favorite in this one, at -225, while the underdog Rockies have +186 odds to upset. San Diego is favored on the run line (-1.5). The over/under is 11 runs for this game (with -117 odds to go over and -103 odds on the under).
Here’s everything you need to know from a betting perspective on the Padres-Rockies game, regarding the run line, moneyline and total, plus expert picks.
Keep up with MLB on FOX Sports.
Padres vs. Twins Highlights | MLB on FOX 
Check out the best moments between the San Diego Padres and Minnesota Twins.
Padres vs. Rockies Game Information & OddsWhen: Friday, September 5, 2025 at 8:40 p.m. ETWhere: Coors Field in Denver, ColoradoHow to watch on TV: COLR and SDPA Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Padres -225 +186 11 -117 -103 -1.5 -160 +134 Padres vs. Rockies PredictionScore Prediction: Padres 6, Rockies 5Total Prediction: Over 11 runsWin Probabilities: Padres 56%, Rockies 44%Padres vs. Rockies Betting InsightsThis season, the Padres have won 44 out of the 75 games, or 58.7%, in which they’ve been favored.San Diego has a record of 2-2 in games when bookmakers favor them by at least -225 on the moneyline.The moneyline for this contest implies a 69.2% chance of a victory for the Padres.The Rockies have been victorious in 38, or 27.9%, of the 136 contests they have been chosen as underdogs in this season.This year, Colorado has won 15 of 69 games when listed as at least +186 or worse on the moneyline.The moneyline set for this matchup implies the Rockies have a 35% chance of walking away with the win.Padres Recent Betting PerformanceThe Padres have a 1-4 record from the five games they were moneyline favorites over their last 10 matchups.Over their last 10 outings, the Padres and their opponents combined to hit the over seven times (all 10 of the games had set totals).The Padres have a 2-8-0 record against the spread over their past 10 games.Padres Recent Stats Stat Avg/Total Record 2-8 Runs Per Game 4.6 HR 12 ERA 5.86 K/9 9.3 Padres Player InsightsFernando Tatis Jr. is batting .262 with 27 doubles, two triples, 19 home runs and 82 walks.In all of MLB, Tatis is 69th in home runs and 103rd in RBI.Manny Machado has shown off his power as he paces his team with 22 home runs and 81 RBI.Machado is 48th in homers and 24th in RBI among all batters in MLB.Machado enters this game looking for his third game in a row with a hit. In his last five games he is hitting .222 with a home run, two walks and three RBIs.Luis Arraez has a team-high batting average of .284.Arraez has at least one base hit in six straight games. During his last 10 games he is hitting .250 with a double, a home run, a walk and five RBIs.Ramon Laureano has hit 22 home runs to lead his team.Laureano takes a five-game streak with at least one hit into this one. In his last five games he is hitting .421 with a home run, two walks and four RBIs.Rockies Recent Betting PerformanceThe Rockies have played as underdogs in 10 of their past 10 games and won two of those contests.When it comes to hitting the over, the Rockies and their opponents are 3-6-1 in their last 10 games with a total.The Rockies have won four of their last 10 games against the spread.Rockies Recent Stats Stat Avg/Total Record 2-8 Runs Per Game 3.9 HR 6 ERA 6.00 K/9 6.9 Rockies Player InsightsHunter Goodman leads the Rockies with 27 home runs and 83 runs batted in, while posting a team-high batting average of .280.Goodman ranks 24th in homers and 21st in RBI among all hitters in the big leagues.Moniak is batting .262 with 17 doubles, eight triples, 18 home runs and 19 walks.Among all major league hitters, Moniak ranks 81st in homers and 110th in RBI.Jordan Beck is hitting .270 with 25 doubles, five triples, 14 home runs and 39 walks.Brenton Doyle has 19 doubles, two triples, 14 home runs and 29 walks while hitting .247.Rockies vs. Astros Highlights | MLB on FOX 
Check out the best moments between the Colorado Rockies and the Houston Astros
FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.
Want great stories delivered right to your inbox? Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.
FOLLOW Follow your favorites to personalize your FOX Sports experience
What did you think of this story?