Data Skrive
Jackson Merrill and the San Diego Padres will hit the field against the Colorado Rockies and Jordan Beck at PETCO Park on Friday at 9:40 p.m. ET. The Padres are -308 moneyline favorites in this matchup against the Rockies (+246). San Diego is a 1.5-run favorite (at -143 odds). The contest’s total has been set at 8 runs.
Here’s everything you need from a betting perspective on the Padres-Rockies game, regarding the run line, moneyline and total, plus expert picks.
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Reds vs. Padres Highlights | MLB on FOX 
Enjoy the best moments between Cincinnati Reds and the San Diego Padres.
Padres vs. Rockies Game Information & OddsWhen: Friday, September 12, 2025 at 9:40 p.m. ETWhere: PETCO Park in San Diego, CaliforniaHow to watch on TV: SDPA and COLR Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Padres -308 +246 8 -106 -114 -1.5 -143 +119 Padres vs. Rockies PredictionScore Prediction: Padres 6, Rockies 4Total Prediction: Over 8 runsWin Probabilities: Padres 62%, Rockies 38%Padres vs. Rockies Betting InsightsThe Padres have entered the game as favorites 82 times this season and won 48, or 58.5%, of those games.San Diego has played as favorites of -308 or more once this season and lost that game.Bookmakers have implied with the moneyline set for this matchup that the Padres have a 75.5% chance to win.The Rockies have been victorious in 39, or 27.3%, of the 143 contests they have been chosen as underdogs in this season.This season, Colorado has come away with a win four times in 24 chances when named as an underdog of at least +246 or longer on the moneyline.The moneyline set for this matchup implies the Rockies have a 28.9% chance of coming away with a victory in the contest.Padres Recent Betting PerformanceThe Padres went 4-6 over the 10 games they were favored on the moneyline in their last 10 matchups.In their last 10 matchups — all had a set run total — the Padres and their opponents combined to hit the over on the total two times.The Padres’ ATS record is 3-7-0 over their past 10 games.Padres Recent Stats Stat Avg/Total Record 4-6 Runs Per Game 3.7 HR 10 ERA 3.50 K/9 10.7 Padres Player InsightsFernando Tatis Jr. is batting .260 with 27 doubles, two triples, 21 home runs and 84 walks.Tatis’ home runs rank him 60th in MLB, and he is 92nd in RBI.Manny Machado has put his power on display as he paces his team with 23 home runs and 84 RBI.Machado is 49th in home runs and 25th in RBI on the season.Luis Arraez has racked up a team-high batting average of .285.Arraez is on a two-game hitting streak entering this contest. During his last five outings he is hitting .235 with two walks and an RBI.Ramon Laureano’s 23 home runs pace his team.Padres Team Props Hits O/U Total Bases O/U HR O/U RBI O/U Ryan O’Hearn – – – – Ramon Laureano – – – – Manny Machado – – – – Luis Arraez – – – – Jake Cronenworth – – – – Rockies Recent Betting PerformanceThe Rockies have played as underdogs in 10 of their past 10 games and have gone 1-9 in those contests.In their last 10 games with a total, the Rockies and their opponents have failed to hit the over six times.The Rockies have a record of 1-9-0 ATS over their last 10 games.Rockies Recent Stats Stat Avg/Total Record 1-9 Runs Per Game 2.9 HR 6 ERA 6.28 K/9 7.6 Rockies Player InsightsHunter Goodman leads the Rockies in home runs (30), runs batted in (87) and has a team-high batting average of .280.Goodman ranks 13th in home runs and 23rd in RBI among all hitters in the majors.Mickey Moniak is batting .262 with 17 doubles, eight triples, 19 home runs and 21 walks.Moniak is currently 76th in home runs and 113th in RBI in the major leagues.Beck is batting .267 with 26 doubles, five triples, 15 home runs and 41 walks.Brenton Doyle is batting .243 with 21 doubles, two triples, 14 home runs and 29 walks.Rockies Team PropsReds vs. Padres Highlights | MLB on FOX
Enjoy the best moments between Cincinnati Reds and the San Diego Padres.
FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.
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