The afternoon slate is packed with 10 games for Week 10, headlined by the New England Patriots and Tampa Bay Buccaneers in the early window and the Los Angeles Rams visiting the San Francisco 49ers in the late afternoon. With six divisional matchups on the day, there are plenty of games with potential playoff implications on the line.
The Patriots (7-2) and Buccaneers (6-2) don’t meet often, but this time they match up as two of the top teams in the NFL. New England leads the series 7-3 all-time, having beaten Tampa four of the last five times they played. The Patriots are winners of six in a row and are coming off a narrow victory over Atlanta last week, 24-23. Second-year quarterback Drake Maye has had an excellent start to his year, leading New England to a surprising lead over the Bills in the AFC East.
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Tampa Bay dominated New Orleans 23-3 in their last game, before last week’s bye. Baker Mayfield is having an MVP-caliber first half of the season, passing for 1,919 yards, 12 touchdowns and 2 interceptions.
Follow along here for live updates on Patriots-Bucs and the rest of the games in the early and afternoon matchups.
Week 10 schedule, how to watch, game times for Sunday
All times listed are ET*
Saints vs. Panthers, 1 p.m. on Fox
Giants vs. Bears, 1 p.m. on Fox
Jaguars vs. Texans, 1 p.m. on CBS
Bills vs. Dolphins, 1 p.m. on CBS
Ravens vs. Vikings, 1 p.m. on Fox
Browns vs. Jets, 1 p.m. on CBS
Patriots vs. Buccaneers, 1 p.m. on CBS
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Cardinals vs. Seahawks, 4:05 p.m. on CBS
Rams vs. 49ers, 4:25 p.m. on Fox
Lions vs. Commanders, 4:25 p.m. on Fox
Teams on a bye: Bengals, Cowboys, Chiefs, Titans
Follow along with Yahoo Sports for live updates, highlights and more from Week 10’s early and afternoon Sunday game slates:
Live67 updatesSun, November 9, 2025 at 2:35 p.m. EST
Kate Magdziuk
With less than 90 minutes remaining until the first games in the afternoon slate kick off, inactives are starting to roll in.
Here’s a full look at the Week 10 inactives for the afternoon games:
Cardinals vs. Seahawks
Cardinals inactives: CB Will Johnson, LB Mack Wilson Sr., CB Max Melton, OL Demontrey Jacobs, OL Josh Fryar, WR Xavier Weaver, DL Bilal Nichols
Seahawks inactives: QB Jalen Milroe, CB Josh Jobe, LB Jared Ivey, LB Ernest Jones IV, WR Tory Horton, OL Mason Richman, WR Jake Bobo
Rams vs. 49ers
Rams inactives: QB Stetson Bennett IV, K Joshua Karty, RB Jarquez Hunter, LS Alex Ward, OL Beaux Limmer, OL D.J. Humphries, DE Desjuan Johnson
49ers inactives: QB Brock Purdy, RB Jordan James, WR Ricky Pearsall, OL Connor Colby, DL Sebastian Valdez, DL Alfred Collins, S Marques Sigle
Lions vs. Commanders
Lions inactives: S Erick Hallett, DL Quinton Jefferson, S Kerby Joseph, DL Pat O’Connor, RB Jacob Saylors, DL Mekhi Wingo
Commanders inactives: QB Jayden Daniels, WR Terry McLaurin, LB Kain Medrano, OT Trent Scott, OT George Fant, DE Jalyn Holmes
Criss Partee
The New York Jets get their second win of the Aaron Glenn era by beating the Cleveland Browns, 27-20. Despite quarterback Justin Fields passing for just 54 yards, the Jets pulled out the victory, getting two special teams touchdowns on returns by Kene Nwangwu and Isaiah Williams. New York improved to 2-7 on the season.
Dillon Gabriel was sacked six times for the Browns, and the Jets’ Quincy Williams was responsible for four of them. Although it wasn’t a great game for Gabriel, completing only 53% of his passes for 167 yards, he did throw two touchdowns. Cleveland falls to 2-7 with the loss.
Kate Magdziuk
Baker Mayfield is the king of game-winning drives this year, but despite a last-minute touchdown to WR Tez Johnson (his second of the game), the Buccaneers weren’t able to mount the fourth-quarter comeback.
Tampa Bay attempted an onside kick, but it was recovered by Patriots receiver Stefon Diggs. Drake May kneeled it out to make their win official.
The Patriots now sit with an 8-2 record and extend their lead in the AFC East after the Dolphins notched a surprising upset over the second-place Bills in Week 10.
Kate Magdziuk
TreVeyon Henderson locked in his second career start in Week 10 with veteran Rhamondre Stevenson ut with a toe injury. Boy, has he delivered.
With just minutes to go in the fourth quarter, Henderson exploded for a 69-yard rushing touchdown to take a 28-16 lead with the successful extra-point attempt — Henderson’s second score of the day.
His first touchdown of the day went for 55 yards. He now has 147 rushing yards on just 14 carries, averaging 10.5 yards per attempt in his second career start.
Criss Partee
New Orleans gets the win over Carolina, 17-7. Saints quarterback Tyler Shough finished with 282 yards and two touchdown passes. Wide receiver Chris Olave had five catches for 104 yards and a touchdown. Tight end Juwan Johnson had four catches for 92 yards and a touchdown.
Bryce Young had a rough day for the Panthers, passing for just 124 yards and an interception. Running back Rico Dowdle was cooled off a bit, rushing for just 53 yards and a touchdown.
Kate Magdziuk
The Miami Dolphins have all but iced the game with a second long touchdown from RB De’Von Achane, as the Bills take a 30-13 lead with a successful extra point attempt.
Achane has 225 scrimmage yards and two touchdowns on the day, averaging 7.9 yards per carry while leading the team with six receptions on the day (51 receiving yards). His 174 rushing yards are the second-most he’s ever had in a career game.
With that lead, the Bills have officially taken Josh Allen out of the game, replacing him with backup quarterback Mitch Trubisky.
Criss Partee
Texans QB Davis Mills finds Jayden Higgins for the touchdown. Mills is 20 of 33 with 1 touchdown and 1 interception, filling in for the injured C.J. Stroud.
Kate Magdziuk
Kate Magdziuk
The New York Giants have ruled out rookie quarterback Jaxson Dart with a concussion, putting veteran Russell Wilson in line to finish out the game.
Prior to his exit, Dart had completed 19 of 29 pass attempts for 242 passing yards, adding another 66 rushing yards and two touchdowns on the ground.
Kate Magdziuk
Just over halfway through the fourth quarter, MVP candidate Drake Maye had an opportunity to extend the Patriots’ lead over the Buccaneers after connecting with WR Mack Hollins on a 54-yard deep ball to set the team up at the goal line.
The opportunity didn’t pan out, though, as Maye threw an interception in the red zone into the arms of Buccaneers safety Tykee Smith.
The Bucs take over possession at their own 20-yard line, down five points with just over four minutes to go in the game.
Criss Partee
Jets running back Breece Hall goes the distance on this screen play for a 42-yard touchdown. Hall has 72 rushing yards and 42 receiving yards in the game. The Jets lead the Browns 27-17.
Kate Magdziuk
Kate Magdziuk
Fantasy football managers had given up on Ravens tight end Mark Andrews, but despite fairly limited usage this year, he’s now scored his fifth touchdown of the season, scoring in his second consecutive game to extend the Ravens’ lead in Week 10.
#ThatHelpsNoOne
Kate Magdziuk
Josh Allen, what happened? A wild quarterback sneak that went for 15 yards results in a … fumble-roooooski?! Just as the Bills were driving following a Tua Tagovailoa interception … tough luck, Buffalo.
It’s another lost fumble for the Bills, recovered by safety Minkah Fitzpatrick. The Dolphins take over at their own 38-yard line with a 10-point lead. There are just over seven minutes remaining in the fourth quarter.
Criss Partee
Saints quarterback Tyler Shough finds Juwan Johnson down the sideline for the 30-yard touchdown.
Kate Magdziuk
The Buffalo Bills aren’t ready to lie down!
Rookie Maxswell Hairston comes up with a fourth-quarter interception on a deep pass attempt from Tua Tagovailoa — his second consecutive game with an interception, with the first coming against Patrick Mahomes in Week 9’s win over the Chiefs.
That now marks Tagovailoa’s fourth game of the year with multiple interceptions.
Criss Partee
Saints cornerback Alontae Taylor picks off Bryce Young for his first interception of the season. This is Taylor’s first interception since the 2023 season.
Kate Magdziuk
Giants starting quarterback Jaxson Dart appeared to hit his head and is currently being evaluated in the medical tent. Russell Wilson is now in at quarterback for New York.
Criss Partee
New York gets to Cleveland quarterback for the fourth time on this Quincy Williams sack. Williams has six total tackles, 1 sack, and 2 tackles for loss in the game. This performance comes on the heels of Williams being benched by head coach Aaron Glenn this week.
Will McDonald IV has four of the Jets’ five sacks on Dillon Gabriel today.
Kate Magdziuk
Buffalo has officially ruled out tight end Dalton Kincaid with a hamstring injury.
Kate Magdziuk
Whew, it was a brutal start for Buffalo in Week 10, failing to score a single point through the first three quarters of the game.
… but it’s never over until it’s over!
Josh Allen and the Bills have begun their attempt at a comeback, opening up the fourth quarter with their first scoring drive of the game.
Allen had three consecutive explosive plays, including a 24-yard pass to WR Tyrell Shavers and a 20-yard pass to TE Dawson Knox, capped off with a 35-yard touchdown to second-year WR Keon Coleman.
Coleman appeared to be off to a red-hot start this year with an 8-112-1 line in Week 1 to open up the season. However, he had failed to exceed 45 yards in a single game since prior to today.
The Bills went for two after the touchdown but were just shy of the goal line on a throw to Khalil Shakir. The Dolphins have a 10-point lead over the Bills with just under 13 minutes to go in the fourth quarter.