The Houston Rockets start a two-game road swing tonight, while the Philadelphia 76ers finish a five-game homestand, looking for just their second win of the stretch.

The Rockets will be without big man Steven Adams, while Philadelphia may get both Joel Embiid and Paul George back into the rotation.

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That’s why my Rockets vs. 76ers  predictions and NBA picks call for Philly to win outright as a home dog on Thursday, January 22.

Rockets vs 76ers prediction

Rockets vs 76ers best bet: 76ers moneyline (+115)

Veteran Houston Rockets center Steven Adams suffered a serious ankle sprain in the last game. “I don’t think he’ll be back anytime soon,” Rockets coach Ime Udoka later said.

Adams leads the NBA in offensive rebounding, so his absence will be felt on a team that is also No. 1 in the league in that category. The Rockets’ No. 6 shot blocking performance will also suffer.

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That lack of a presence in the paint will be a problem, as the Philadelphia 76ers should welcome Joel Embiid back after he missed the last game with an ankle injury.

There’s also a chance Philly gets Paul George back. He’s missed two games with a knee injury and is questionable. The Sixers are just 4-7 this season with neither in the lineup, and seven games over .500 with one or both active.

Regression to the mean should work in Philly’s favor.

Tyrese Maxey, shooting 47% and 40% from three this season, has hit 33 of 88 — 7 of 28 from three — over the last four. He’s ripe for a bounce back, especially with two other scorers in the lineup to help draw attention away from him.

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Rockets vs 76ers same-game parlay

The Rockets have gone under in nine of their last 10 games. They are 28th in pace, while the Sixers are 19th.

This cutoff is in line with what Houston has been seeing recently, however. The Rockets faced four Over/Unders this low in the last 10 games and went Under on all of them. Philly faced two this low in its last 10 and split.

Amen Thompson has 34 rebounds in his last four games, nearly one rebound per game higher than his season average. And that was with Adams in the paint. With Adams out, he’s unlikely to see his workload on the boards go down.

Rockets vs 76ers SGP

Amen Thompson Over 7.5 rebounds

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Our “from downtown” SGP: By George, He’s Still Got It

George playing is the big question mark here, and if he doesn’t, this pushes. So we’ll take him reaching 15 if he suits up.

Rockets vs 76ers SGP

Amen Thompson Over 7.5 rebounds

Paul George Over 14.5 points

Rockets vs 76ers odds

Spread: Rockets -2 (-110) | 76ers 2 (-110)

Moneyline: Rockets -135 | 76ers +115

Over/Under: Over 221.5 (-110) | Under 221.5 (-110)

Rockets vs 76ers betting trend to know

The Houston Rockets have only hit the Moneyline in 20 of their last 45 away games. Find more NBA betting trends for Rockets vs. 76ers.

How to watch Rockets vs 76ers

Location

Xfinity Mobile Arena, Philadelphia, PA

Date

Thursday, January 22, 2026

Tip-off

7:00 p.m. ET

TV

NBCS-Philadelphia, SCHN

Rockets vs 76ers latest injuries

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