The Saskatchewan Roughriders will travel to McMahon Stadium to face the Calgary Stampeders on Saturday night. This Week 12 matchup in the CFL features the top two teams in the West going into this week’s action. Both sides have star power and this game is a pick ’em in the betting markets. Before this Week 12 headliner in the CFL, continue reading to get my Roughriders vs Stampeders prediction.

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Game SnapshotMatchup: Saskatchewan Roughriders vs Calgary StampedersDate & Time: Saturday, August 23, 2025, 7:00 p.m. ETVenue: McMahon Stadium, CalgaryBroadcast: TSNRoughriders vs Stampeders OddsOddsValueSpreadPick ’emMoneylineRoughriders –110, Stampeders –110Total50.5Key StorylinesRecent form

Saskatchewan is the league’s best team at 8-1. The Roughriders have the best scoring defense in the CFL at 20.3 points per game through Week 11. They are riding a four-game winning streak since a 24-10 loss at home to Calgary in Week 6. They will look to avenge that loss against a Calgary that is sitting at 6-3.

Calgary got a 28-27 over the Winnipeg Blue Bombers in Vernon Adams Jr.’s return to the field after he missed a game due to injury. Both of these teams are largely healthy going into this important matchup and will look to make a statement of intent in the West division race.

Quarterback play

Trevor Harris is back from injury and gives the Roughriders offensive stability at quarterback. He is fourth in the league in passing yards despite missing a game this year. He is tied for third in passing touchdowns with 16.

Vernon Adams Jr. is orchestrating Calgary’s dynamic offense. He has also missed time this season but has thrown for over 2,000 yards and there was a clear difference in the quality of the Stamps’ offense with Adams and without him.

Betting Trends & H2HSaskatchewan has won four games in a row going into Week 12.The Roughriders are 8-1 straight up and 7-2 against the spread this season.The Stampeders are 6-3 straight up and 5-4 against the spread on the year.Both teams are 4-5 in the over/under market this season. Just over half of their games have stayed under their totals.Roughriders vs Stampeders Model Projection

Score Projection: Saskatchewan Roughriders 28 – Calgary Stampeders 24

Win Probability: Saskatchewan 58%, Calgary 42%

Final Thoughts

We should see a tight game between the top two teams in the West here. The return of Vernon Adams Jr. gave the Stamps a huge boost offensively in their last game. But I’m not sure that will be enough for the Stampeders to get a win in this contest against the best defensive team in the CFL. I’ll take the Riders to win this pick ’em contest on the road.

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