NFL Week 4 betting lines and prediction for Colts v. Commanders
Sept. 29, 2026, 7:08 a.m. ET
Next up for the Indianapolis Colts is a Week 4 matchup in London against the Washington Commanders.
Both teams will enter this game at 1-2 on the season, with each coming off their first win of the year — the Colts defeating the Houston Texans and the Commanders beating the Seattle Seahawks.
When it comes to the early betting lines, the Colts are the overseas favorites in this game.
Colts vs. Commanders Week 4 betting odds, moneyline, over/underColts vs. Commanders prediction
According to ESPN analytics, the Colts have a 54.4% chance of winning this matchup.
Your fantasy edge starts here Sync your league for custom roster advice, projections, and tools to win your matchups every week.How to watch Colts vs. CommandersWhen: Sunday, Oct. 4Where: Tottenham Hotspur StadiumKickoff: 9:30 AM ETChannel: NFL NetworkColts’ Steichen evaluates Sauce Gardner’s early impact (Link)Injury updates on Colts’ Laiatu Latu, others after Week 3 win (Link)Colts Daniel Jones evaluates performance vs. Texans (Link)Colts Week 3 snap counts: A disruptive day for Adetomiwa Adebawore (Link)
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