Evolutionary causes and consequences of gene duplication
Kuzmin, E., Taylor, J. S. & Boone, C. Retention of duplicated genes in evolution. Trends Genet. 38, 59–72…
X chromosome inactivation across primary human tissues is mostly complete, with significant implications for genetic and clinical studies | BMC Genomics
Lyon MF. Gene action in the X-chromosome of the mouse (Mus musculus L). Nature. 1961;190:372–3. Google Scholar Berletch…
The whole-genome map of Astragalus mongholicus provides ideas for the synthesis of glutathione and flavonoid | BMC Genomics
Fu J, Wang Z, Huang L, Zheng S, Wang D, Chen S, et al. Review of the botanical…
Harnessing artificial intelligence to advance CRISPR-based genome editing technologies
Zheng, Y. et al. Precise genome-editing in human diseases: mechanisms, strategies and applications. Signal. Transduct. Target. Ther. 9,…
Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function
Institute of Medical Genetics, University of Zurich, Zurich, Switzerland Reza Asadollahi, Paranchai Boonsawat, Dennis Kraemer & Anita Rauch Faculty of Engineering and…
Natural selection exerted by historical coronavirus epidemic(s): comparative genetic analysis in China Kadoorie Biobank and UK Biobank | BMC Genomics
AppendixMethodsStatistics and reproducibility The details of each analysis are outlined in the methods section and all of the…
Modeling heterogeneity in single-cell perturbation states enhances detection of response eQTLs
Cohorts We used published data (GEO accession no. GSE162632) to study the effect of 12 h of ex vivo…
Genotyping sequence-resolved copy number variation using pangenomes reveals paralog-specific global diversity and expression divergence of duplicated genes
Overview of the genotyping method We represent variation as haplotype segments that are short enough to minimize disruption…
Redefining cellular reprogramming with advanced genomic technologies
Briggs, R. & King, T. J. Transplantation of living nuclei from blastula cells into enucleated Frogs’ eggs. Proc.…
Meta-analysis reveals differences in somatic alterations by genetic ancestry across common cancers
Genetic ancestry is a quantitative measure of inherited genetic variation and correlates with human migration patterns1. It contributes…
SPAmix: a scalable, accurate, and universal analysis framework for large-scale genetic association studies in admixed populations | Genome Biology
Model residuals of linear regression and logistic regression Linear regression and logistic regression are regular models to fit…
Genetic variation and genome-enabled selection of white lupin for key seed quality traits | BMC Genomics
Foyer CH, Lam H-M, Nguyen HT, Siddique KHM, Varshney RK, Colmer TD, et al. Neglecting legumes has compromised…