Disrupted brain-immune signaling may help drive neurodegeneration
From gut-primed T cells to microglial signaling and persistent gene-regulatory states, researchers map an intricate immune network that…
First-in-class experimental CAR T-cell therapy shows promise against solid tumors
Researchers with the Charbonneau Cancer Institute at the University of Calgary and McMaster University have identified a unique…
Kenyan bat coronavirus uses human CEACAM6 to enter cells, raising spillover concerns
A newly characterized bat coronavirus can latch onto a human cell receptor found in the lung, giving scientists…
Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study
A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the possibility that engineered immune…
Silica nanomatrix enhances immunotherapy for solid tumors
Cancer has long remained a leading cause of death worldwide and in Hong Kong, accounting for 30% of…
Engineered extracellular vesicles enable antigen-specific regulatory T cell induction
A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University…
Genetic modification enhances “living drugs” for blood cancers
CAR T cells are patient-derived, genetically engineered immune cells. They are “living drugs” and constitute a milestone in…