New spatial omics platform advances biomedical research in Spain
Spatial omics is a new generation of technologies that allow scientists to study cells in their original location…
Experiencing acute genomic care: perspectives from parents in the neonatal and paediatric intensive care units towards rapid genomic sequencing
Kingsmore SF, Nofsinger R, Ellsworth K. Rapid genomic sequencing for genetic disease diagnosis and therapy in intensive care…
Silica nanoparticles suppress fungal pathogenic allies to alleviate Astragalus root rot | Microbiome
Dutta P, Kumari A, Mahanta M, Upamanya Gunadhya K, Heisnam P et al. Nanotechnological approaches for management of…
World Record Set For Fastest Genome Sequencing | Health
Key Takeaways Researchers have set a new world record for fastest whole human genome sequencing The team completed…
SPAmix: a scalable, accurate, and universal analysis framework for large-scale genetic association studies in admixed populations | Genome Biology
Model residuals of linear regression and logistic regression Linear regression and logistic regression are regular models to fit…
SAGPEK: fast and flexible approach to identify genotypes of Sanger sequencing data | BMC Bioinformatics
Software architecture SAGPEK mainly processes Sanger sequencing results of two kinds of samples: diploids such as humans and…
A novel gene expression stability metric to unveil homeostasis and regulation | Genome Biology
K-proportion and gene homeostasis Z-Index identify regulatory genes As cells of the same type and in the same…
‘Google for DNA’ brings order to biology’s big data
MetaGraph indexes and vast archives of DNA, RNA, and protein sequences. Scientists can search the archives and trace…
Incorporating additive genetic effects and linkage disequilibrium information to discover gene-environment interactions using BV-LDER-GE | Genome Biology
Model overview We consider the following model to incorporate both additive and interaction effects: $${Y}_{i}={\sum }_{j=1}^{M}{G}_{ji}{\beta }_{j}+{\sum }_{j=1}^{M}{S}_{ji}{\gamma…
Advances in haplotype phasing and genotype imputation
Voight, B. F., Kudaravalli, S., Wen, X. & Pritchard, J. K. A map of recent positive selection in…
Genomenon and Compass Bioinformatics Partner to Transform Genomic Diagnostics in the U.S. and Japan
Mastermind® FLEX Data powers Compass Bioinformatics’s InheriNext® platform, bringing unparalleled genomic evidence to leading institutes across US, Japan,…
Fueling chromosomal gene diversification and artificial evolution with CRISPR | Genome Biology
Wilson DS, Keefe AD. Random mutagenesis by PCR. Curr Protoc Mol Biol. 2001;51:8–3. Google Scholar Reetz MT, Wu…