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Browsing Tag

bioinformatics

13 posts
GGenetics
Genomenon and Compass Bioinformatics Partner to Transform Genomic Diagnostics in the U.S. and Japan
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Genomenon and Compass Bioinformatics Partner to Transform Genomic Diagnostics in the U.S. and Japan

  • September 23, 2025
Mastermind® FLEX Data powers Compass Bioinformatics’s InheriNext® platform, bringing unparalleled genomic evidence to leading institutes across US, Japan,…
GGenetics
Fueling chromosomal gene diversification and artificial evolution with CRISPR | Genome Biology
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Fueling chromosomal gene diversification and artificial evolution with CRISPR | Genome Biology

  • September 23, 2025
Wilson DS, Keefe AD. Random mutagenesis by PCR. Curr Protoc Mol Biol. 2001;51:8–3. Google Scholar  Reetz MT, Wu…
GGenetics
Regulation of heterosis-associated gene expression complementation in maize hybrids | Genome Biology
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Regulation of heterosis-associated gene expression complementation in maize hybrids | Genome Biology

  • September 22, 2025
Plant genetic resources The IBM-RIL syn. 4 population [19] represents a collection of highly diversified genotypes with respect…
GGenetics
Systema: a framework for evaluating genetic perturbation response prediction beyond systematic variation
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Systema: a framework for evaluating genetic perturbation response prediction beyond systematic variation

  • August 25, 2025
Nonparametric baselines We design two nonparametric baselines that we refer to as perturbed mean and matching mean. Perturbed…
GGenetics
The genetic history of Portugal over the past 5,000 years | Genome Biology
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The genetic history of Portugal over the past 5,000 years | Genome Biology

  • August 20, 2025
Gómez-Carballa, A., Olivieri, A., Behar, D.M., Achilli, A., Torroni, A., and Salas, A. . Genetic Continuity in the…
GGenetics
GeneRiskCalc: a web-based tool for genetic risk association analysis in case–control studies | BMC Bioinformatics
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GeneRiskCalc: a web-based tool for genetic risk association analysis in case–control studies | BMC Bioinformatics

  • August 19, 2025
Hardy–Weinberg equilibrium The HWE is a key principle in population genetics, stating that allele and genotype frequencies remain…
GGenetics
GenMasterTable: a user-friendly desktop application for filtering, summarising, and visualising large-scale annotated genetic variants | BMC Bioinformatics
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GenMasterTable: a user-friendly desktop application for filtering, summarising, and visualising large-scale annotated genetic variants | BMC Bioinformatics

  • August 13, 2025
GenMasterTable is a standalone, cross-platform desktop application developed in Python to facilitate scalable genomic data analysis. It integrates…
GGenetics
Morphological map of under- and overexpression of genes in human cells
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Morphological map of under- and overexpression of genes in human cells

  • August 7, 2025
Mattiazzi Usaj, M. et al. High-content screening for quantitative cell biology. Trends Cell Biol. 26, 598–611 (2016). CAS …
GGenetics
The Platinum Pedigree: a long-read benchmark for genetic variants
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The Platinum Pedigree: a long-read benchmark for genetic variants

  • August 5, 2025
Gonzaga-Jauregui, C., Lupski, J. R. & Gibbs, R. A. Human genome sequencing in health and disease. Annu. Rev.…
GGenetics
Deep-learning-based gene perturbation effect prediction does not yet outperform simple linear baselines
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Deep-learning-based gene perturbation effect prediction does not yet outperform simple linear baselines

  • August 4, 2025
The success of large language models in knowledge representation has spawned efforts to apply the foundation model concept…
GGenetics
Urbanization and genetic homogenization in the medieval Low Countries revealed through a ten-century paleogenomic study of the city of Sint-Truiden | Genome Biology
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Urbanization and genetic homogenization in the medieval Low Countries revealed through a ten-century paleogenomic study of the city of Sint-Truiden | Genome Biology

  • August 4, 2025
Lawson DJ, Hellenthal G, Myers S, Falush D. Inference of Population Structure using Dense Haplotype Data. Copenhaver GP,…
GGenetics
GeneAgent: self-verification language agent for gene-set analysis using domain databases
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GeneAgent: self-verification language agent for gene-set analysis using domain databases

  • August 2, 2025
Model setting and data collection In this work, we utilized GPT-4 (version 20230613) as the backend model via…
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