Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health
Ethics Our research complies with all relevant ethical regulations. All studies included in this research were approved by…
Association between daily dietary intake trajectory and depressive symptom onset and transition among young adults: a longitudinal study | BMC Medicine
Baseline characteristics As shown in Table 1, we included 6447 young adults, of whom 3040 (47.2%) were female; 3407…
STI testing and diagnosis rates among patients with Mpox in 2 populous US cities, 2022 | BMC Medicine
Patient consent This study was approved by the Columbia University Irving Medical Center Institutional Review Board, with a…
Generative artificial intelligence in medicine
Bengesi, S. et al. Advancements in generative AI: a comprehensive review of GANs, GPT, autoencoders, diffusion model, and…
Changes in frailty, intensive blood pressure treatment, and risks of adverse clinical outcomes: a post hoc analysis of the SPRINT trial | BMC Medicine
Study design and population This is a post hoc analysis of the SPRINT, an open-label randomized controlled clinical…
A genetic map of human metabolism across the allele frequency spectrum
Study design The UKB is a prospective cohort study from the UK that contains more than 500,000 volunteers…
Early life adversity and risk for non-communicable health outcomes: challenges and opportunities for a maturing field | BMC Medicine
Early life adversity has a profound and life-long impact on health and development, initiating a cascade of dysregulations…
Operationalizing machine-assisted translation in healthcare
Rawal, S. et al. Association between limited English proficiency and revisits and readmissions after hospitalization for patients with…
Spatial architecture of development and disease
Bressan, D., Battistoni, G. & Hannon, G. J. The dawn of spatial omics. Science 381, eabq4964 (2023). Article …
Limited overlap between genetic effects on disease susceptibility and disease survival
Ethics statement This study was conducted in compliance with the relevant ethical guidelines and approved by the appropriate…
Advances in haplotype phasing and genotype imputation
Voight, B. F., Kudaravalli, S., Wen, X. & Pritchard, J. K. A map of recent positive selection in…
The dawn of bryophyte genomics is here
Puttick, M. N. et al. Curr. Biol. 28, 733–745.e2 (2018). Article PubMed CAS Google Scholar Shaw, A. J,…