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Browsing Tag

Biomedicine

75 posts
HHealthcare
Systematic review of cost effectiveness and budget impact of artificial intelligence in healthcare
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Systematic review of cost effectiveness and budget impact of artificial intelligence in healthcare

  • August 28, 2025
This systematic review synthesized economic evidence from 19 diverse clinical AI interventions across multiple specialties, demonstrating consistent clinical…
HHealth
Optimizing pharmacologic treatment for neonatal opioid withdrawal syndrome (OPTimize NOW): a symptom-based dosing approach study protocol for a multi-center, cluster crossover design randomized controlled trial | Trials
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Optimizing pharmacologic treatment for neonatal opioid withdrawal syndrome (OPTimize NOW): a symptom-based dosing approach study protocol for a multi-center, cluster crossover design randomized controlled trial | Trials

  • August 27, 2025
Overview This section briefly describes the analysis plan that will be followed for this study. A statistical analysis…
FFitness
New perspectives on molecular mechanisms underlying exercise-induced benefits in Parkinson’s disease
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New perspectives on molecular mechanisms underlying exercise-induced benefits in Parkinson’s disease

  • August 26, 2025
Poewe, W. et al. Parkinson disease. Nat. Rev. Dis. Prim. 3, 17013 (2017). PubMed  Google Scholar  Stocchi, F.…
GGenetics
Interplay of genetic predisposition, plasma metabolome and Mediterranean diet in dementia risk and cognitive function
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Interplay of genetic predisposition, plasma metabolome and Mediterranean diet in dementia risk and cognitive function

  • August 26, 2025
Ethics statement This study included de-identified data from participants who had consented to the use of their anonymized…
HHealthcare
Cost minimization analysis of digital-first healthcare pathways in primary care
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Cost minimization analysis of digital-first healthcare pathways in primary care

  • August 25, 2025
In our study setting common minor acute primary care episodes initiated via a digital-first pathway were associated with…
GGenetics
Systema: a framework for evaluating genetic perturbation response prediction beyond systematic variation
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Systema: a framework for evaluating genetic perturbation response prediction beyond systematic variation

  • August 25, 2025
Nonparametric baselines We design two nonparametric baselines that we refer to as perturbed mean and matching mean. Perturbed…
GGenetics
Precise modulation of BRG1 levels reveals features of mSWI/SNF dosage sensitivity
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Precise modulation of BRG1 levels reveals features of mSWI/SNF dosage sensitivity

  • August 25, 2025
BRG1 binding exhibits a linear response to its dosage In mES cells, Brg1 encodes the major catalytic subunit…
GGenetics
Temporal genomic dynamics shape clinical trajectory in multiple myeloma
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Temporal genomic dynamics shape clinical trajectory in multiple myeloma

  • August 23, 2025
Maura, F. et al. Moving from cancer burden to cancer genomics for smoldering myeloma: a review. JAMA Oncol.…
HHealth
Incident arrhythmias in relation to ventilatory parameters and pulmonary disease: evidence from two prospective cohort studies | BMC Medicine
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Incident arrhythmias in relation to ventilatory parameters and pulmonary disease: evidence from two prospective cohort studies | BMC Medicine

  • August 22, 2025
Study population The study included subjects from two cohorts, the ARIC (Atherosclerosis Risk in Communities) and the CHS…
GGenetics
Imaging-based multimodal profiling of single cells with STAMP
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Imaging-based multimodal profiling of single cells with STAMP

  • August 22, 2025
Single-cell RNA sequencing (scRNA-seq) has dramatically advanced our ability to dissect complex biological systems at cellular resolution. However,…
GGenetics
KidneyGenAfrica, a pan-African partnership to deliver research and training excellence in genomics of kidney disease
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KidneyGenAfrica, a pan-African partnership to deliver research and training excellence in genomics of kidney disease

  • August 22, 2025
Precision Healthcare University Research Institute, Queen Mary University of London, London, UK Segun Fatumo, Oyesola Ojewunmi, Rebecca Camenzuli, Christopher Kintu & Claudia Langenberg…
GGenetics
Genetic and molecular landscape of comorbidities in people living with HIV
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Genetic and molecular landscape of comorbidities in people living with HIV

  • August 21, 2025
Participants from the 2000HIV study The 2000HIV study is a prospective multicentric observational longitudinal cohort of virally suppressed…
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