Targeting cyclin-dependent kinases offers new pathways for cancer therapy
Cancer is the second leading cause of death in Germany. In the search for new therapeutic approaches that…
ESCRT-III proteins play an unexpected role in protecting DNA bridges during cell division
Every time a cell divides, it must accurately copy and distribute its DNA between two new cells. However,…
Dual pathways found for centromere specification, ensuring accurate chromosome segregation
Despite the immense amount of genetic material present in each cell, around three billion base pairs in humans,…
Study reveals a therapeutic vulnerability in aggressive subtype of triple-negative breast cancer
Dec 26 2025 A new study published today in Science Translational Medicine by researchers at The University of…
Study reveals ATM kinase as the key driver of replicative senescence
After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the…
New insights reveal persistent genome structure during cell division
Before cells can divide, they first need to replicate all of their chromosomes, so that each of the…