From caffeine to trigonelline, coffee has surprising links to muscle biology
From NAD+ metabolism and glucose uptake to muscle mass and frailty, researchers mapped how coffee and its compounds…
Targeting cyclin-dependent kinases offers new pathways for cancer therapy
Cancer is the second leading cause of death in Germany. In the search for new therapeutic approaches that…
Disrupted brain-immune signaling may help drive neurodegeneration
From gut-primed T cells to microglial signaling and persistent gene-regulatory states, researchers map an intricate immune network that…
Wake-activated brain circuits reveal what drives the urge to sleep
By mapping the brain during prolonged wakefulness, researchers pinpointed neuronal populations whose activity rises with time awake and…
Researchers develop custom electronic skin for advanced prosthetic sensing
An electronic skin with a sensing system that can detect pressure and temperature could someday be used to…
Immune signaling pathway protects newborn heart cells from injury
Researchers at the University Hospital of Bonn (UKB) and the University of Bonn have identified a previously unknown…
Natural hormone activates brain-to-liver signaling pathway to suppress liver inflammation
Researchers at McMaster University have discovered that a naturally occurring hormone best known for suppressing appetite and promoting weight…
Thinning cancer cells’ sugar coating could expose tumors to immune attack
Like spies evading detection through being masters of disguise, many cancer cells are adorned with a copious coat…
Fruit fly gut cells track hunger using internal cell viscosity
Researchers led by Sa Kan Yoo at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan have discovered that…
Scientists map key differences in stem cell potency for treating knee osteoarthritis
Knee osteoarthritis (KOA) affects more than 1 in 10 people over 40 years of age, impairing patients’ mobility…
LMU researchers reveal how different organs customize their internal clocks
LMU researchers have elucidated how different organs adapt the same clock machinery to regulate their individual needs over…
Insilico Medicine highlights AI-powered biological target discovery for rare sinonasal cancer
Insilico Medicine (“Insilico”), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced the publication of a collaborative…