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Browsing Tag

CNS cancer

5 posts
NNutrition
Low carbohydrate high fat diet curbs glioblastoma by shifting lipids and limiting cancer stem cell metabolic flexibility
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Low carbohydrate high fat diet curbs glioblastoma by shifting lipids and limiting cancer stem cell metabolic flexibility

  • July 28, 2026
Metabolic rewiring fuels tumorigenicity of cancer stem cells contributing to universal glioblastoma (GBM) recurrence. Invasive glioblastoma stem cells…
HHealth
Dual tumour–myeloid targeting of glioblastoma with GPNMB CAR-T cells
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Dual tumour–myeloid targeting of glioblastoma with GPNMB CAR-T cells

  • July 2, 2026
Cell lines and patient-derived GSC cultures Human GBM samples were obtained from patients who provided written informed consent…
TTechnology
Spatially resolved single-cell analyses of human meningioma identify novel cell states influencing tumor microenvironment and progression
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Spatially resolved single-cell analyses of human meningioma identify novel cell states influencing tumor microenvironment and progression

  • June 10, 2026
Study cohort Our cohort focused on snRNA-seq (n = 102 samples and 580,185 high-quality nuclei) and spatial transcriptomics (Visium HD,…
HHealth
Dominant clones leverage developmental epigenomic states to drive ependymoma
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Dominant clones leverage developmental epigenomic states to drive ependymoma

  • March 25, 2026
In utero electroporation All animal procedures in this study were performed with approval from the St. Jude Institutional…
GGenetics
Systematic decoding of functional enhancer connectomes and risk variants in human glioma
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Systematic decoding of functional enhancer connectomes and risk variants in human glioma

  • August 20, 2025
The study was approved by the Ethics Institutional Review Boards of the First Affiliated Hospital of Sun Yat-sen…
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