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Browsing Tag

Computational biology and bioinformatics

8 posts
SScience
Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle
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Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle

  • July 3, 2026
López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M. & Kroemer, G. The hallmarks of aging. Cell 153,…
TTechnology
Spatially resolved single-cell analyses of human meningioma identify novel cell states influencing tumor microenvironment and progression
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Spatially resolved single-cell analyses of human meningioma identify novel cell states influencing tumor microenvironment and progression

  • June 10, 2026
Study cohort Our cohort focused on snRNA-seq (n = 102 samples and 580,185 high-quality nuclei) and spatial transcriptomics (Visium HD,…
NNutrition
NutriMatch: harmonizing food composition databases with large language models for enhanced nutritional prediction
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NutriMatch: harmonizing food composition databases with large language models for enhanced nutritional prediction

  • January 23, 2026
Data collection We utilized data from the 10K Project, a prospective human cohort study involving over 10,000 healthy…
IInternet
Adaptive resource aware and privacy preserving federated edge learning framework for real time internet of medical things applications
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Adaptive resource aware and privacy preserving federated edge learning framework for real time internet of medical things applications

  • October 21, 2025
The proposed Adaptive Federated Edge Learning (AFEL) framework is designed to address fundamental challenges in Internet of Medical…
SScience
Loss of macroevolutionary species fitness explains the rise and fall of clades
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Loss of macroevolutionary species fitness explains the rise and fall of clades

  • October 18, 2025
Raup, D. M. Biological extinction in Earth history. Science 231, 1528–1533 (1986). Article  CAS  PubMed  Google Scholar  Benton,…
GGenetics
Spatial architecture of development and disease
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Spatial architecture of development and disease

  • October 1, 2025
Bressan, D., Battistoni, G. & Hannon, G. J. The dawn of spatial omics. Science 381, eabq4964 (2023). Article …
GGenetics
CRISPR-GPT for agentic automation of gene-editing experiments
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CRISPR-GPT for agentic automation of gene-editing experiments

  • August 13, 2025
Building AI co-pilot harnessing LLM’s reasoning ability CRISPR-GPT supports four major gene-editing modalities and 22 gene-editing experiment tasks…
GGenetics
Predicting resistance to chemotherapy using chromosomal instability signatures
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Predicting resistance to chemotherapy using chromosomal instability signatures

  • August 2, 2025
CIN signatures as biomarkers of chemotherapy resistance The presence of CIN in a tumor has long been recognized…
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