New polygenic risk scores improve prediction of metabolic disease outcomes
Type 2 diabetes (T2D) and obesity are metabolic conditions with many causes, including overlapping and distinct genetic features.…
New CRISPR technique boosts mitochondrial function to treat heart failure
After a heart attack, the heart struggles to recoup and maintain energy. One third of patients develop heart…
New diagnostic system leverages AI to help fight hospital-acquired infections
An AI tool developed by U of T Engineering professor Nicole Weckman (ISTEP, ChemE) can quickly diagnose infections…
AI‑Designed Anti‑CRISPRs Enable Rapid Cas13 Inhibition
Credit: Meletios Verras/Getty Images Last year’s landmark case of “Baby KJ”—the first patient to receive a personalized CRISPR‑based…
Engineering muscle stem cells for sustainable cultured meat production
The production of cultured meat depends on the isolation, expansion, and differentiation of animal stem cells into edible…
Epigenetic editing enables safer and more effective T cell therapies
Arc Institute, Gladstone Institutes, and University of California, San Francisco, scientists have developed an epigenetic editing platform that…
A Rogue Gene Explains Mysterious Cases of Diabetes and Epilepsy in Newborns
Credit: Wikimedia Commons When six infants around the world were diagnosed with an odd trio of symptoms (diabetes,…
After 1- and 6-Month Gains, Gene Editing Companies Await Q3 Results
As developers of gene editing therapies and other genetic medicines get set to report third quarter earnings in…
Scientists Create a Banana That Doesn’t Turn Brown
Image credits: Matt L. Any banana you eat today is probably a clone. You may have noticed it…
Reporter’s Notebook: The Overdue Breakout for Gene Therapy and Gene Editing
As gene editing enters a new era, leaders discuss Baby KJ’s implications for families, science, and industry. (Left…
Always Fatal Huntington’s Disease is Successfully Treated for First Time With Gene Therapy
Co-founders of the UCL Huntington’s Disease Centre – Professors Tabrizi and Wild There is no cure for Huntington’s…
Scientists Just Made CRISPR 3x More Effective at Treating Genetic Diseases
Illustration of spherical nucleic acid SNA nanoparticle carrying CRISPR cargo – Image by the Mirkin Research Group University…