AI Can Detect Hidden Signs of Aging in the 3D Architecture of DNA
A new AI tool can read hidden signatures of aging from ordinary microscopy images of blood-forming stem cells.…
Identifying critical lysines in mammalian histone H3 with high-throughput CRISPR prime editing
Adapting prime editing for mammalian histone mutagenesis Mouse canonical histone H3 is encoded by nine H3.1 and three…
Scientists find hundreds of inherited DNA patterns that defy classic Mendelian genetics
For more than a century, heredity has been framed through the tidy logic of Mendel’s pea plants: traits…
Penn engineers use AI to solve some of science’s most difficult math problems
A ripple tells you something happened, but not exactly what. That is the core problem behind a hard…
Estrogen loss after menopause impacts heart health through gene regulation
Virginia Tech scientists at the Fralin Biomedical Research Institute say the increased risk of cardiovascular disease after menopause…
New Research Links Daily Multivitamins to Slower Biological Aging
In a randomized clinical trial of older adults, researchers found that taking multivitamins for two years modestly slowed…
ARPA-H-funded PROSPR program focuses on the biological hallmarks of aging
Columbia University Mailman School of Public Health has received an award as part of the PROactive Solutions for Prolonging Resilience (PROSPR) program within the Advanced…
The Surprising Way Parents Transfer Longevity to Offspring
Research in C. elegans shows that longevity-related changes in lysosomes can be passed from parents to offspring. The…
Epigenetic Mechanisms Explain Inheritance of Longevity Markers in C. Elegans
New research in C. elegans from scientists at Howard Hughes Medical Institute (HHMI) helps explain how changes in…
UH study finds gut bacteria linked to how genes switch on and off : Kauai Now
The trillions of microbes that live in the human gut may play a larger role in health than…
Living Descendants Provide Clues to the Genius’s Genetic Secrets
For centuries, Leonardo da Vinci’s genius has fascinated historians and scientists alike, but now researchers are closer than…
Unravelling the genetics and epigenetics of the ageing tumour microenvironment in cancer
de Magalhaes, J. P. How ageing processes influence cancer. Nat. Rev. Cancer 13, 357–365 (2013). Article PubMed Google…