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Browsing Tag

Functional genomics

5 posts
GGenetics
Fueling chromosomal gene diversification and artificial evolution with CRISPR | Genome Biology
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Fueling chromosomal gene diversification and artificial evolution with CRISPR | Genome Biology

  • September 23, 2025
Wilson DS, Keefe AD. Random mutagenesis by PCR. Curr Protoc Mol Biol. 2001;51:8–3. Google Scholar  Reetz MT, Wu…
GGenetics
Clarifying Uncertain Genetic Tests in Cancer Treatment
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Clarifying Uncertain Genetic Tests in Cancer Treatment

  • September 5, 2025
Cancer treatment is becoming more personalised. By considering a patient’s unique genetic and molecular profile, along with their…
GGenetics
Genetic variation at transcription factor binding sites largely explains phenotypic heritability in maize
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Genetic variation at transcription factor binding sites largely explains phenotypic heritability in maize

  • August 12, 2025
Quantification of functional cis-variation To focus on genetic differences affecting TF binding in cis, we quantified TF footprints…
GGenetics
Single-nucleus chromatin accessibility profiling identifies cell types and functional variants contributing to major depression
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Single-nucleus chromatin accessibility profiling identifies cell types and functional variants contributing to major depression

  • August 6, 2025
James, S. L. et al. Global, regional, and national incidence, prevalence, and years lived with disability for 354…
GGenetics
Methods and applications of in vivo CRISPR screening
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Methods and applications of in vivo CRISPR screening

  • July 29, 2025
Auton, A. et al. A global reference for human genetic variation. Nature 526, 68–74 (2015). Google Scholar  García-García,…
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