Single-cell proteomic analysis uncovers hidden layers of blood cell formation
In the past decade there has been significant interest in studying the expression of our genetic code down…
Systema: a framework for evaluating genetic perturbation response prediction beyond systematic variation
Nonparametric baselines We design two nonparametric baselines that we refer to as perturbed mean and matching mean. Perturbed…
Looking beyond suspect genes in cancer
The data analysis center at Fred Hutch/UW are co-led by Sun and Li Hsu, PhD, a biostatistician who…
ChronODE method offers precision in timing gene therapy treatments
A Yale research team has created a new computer tool that can pinpoint when exactly genes turn on…
Ancient viral DNA may play a key role in early human development, new study suggests
The human genome is made up of 23 pairs of chromosomes, the biological blueprints that make humans ……
Scientists link brain lithium loss to early Alzheimer’s changes
A new study reveals that brain lithium depletion occurs early in Alzheimer’s and fuels disease progression, while low-dose…
Unveiling genetic signatures of immune response in immune-related diseases through single-cell eQTL analysis across diverse conditions
Overview of cohort and single-cell RNA-seq data Totally, 325 healthy volunteers were included in the 300BCG vaccination cohort18.…
Ancient viral DNA found to regulate human gene expression
A new international study suggests that ancient viral DNA embedded in our genome, which were long dismissed as…