New polygenic risk scores improve prediction of metabolic disease outcomes
Type 2 diabetes (T2D) and obesity are metabolic conditions with many causes, including overlapping and distinct genetic features.…
Transposable elements cause majority of lethal mutations in fruit flies
Most lethal mutations in wild fruit flies are driven by newly transferred jumping genes, not small DNA errors,…
Long-read whole genome sequencing uncovers new genetic variants linked to autism
Researchers at the University of California San Diego have identified new genetic variants associated with autism spectrum disorder…
New CRISPR technique boosts mitochondrial function to treat heart failure
After a heart attack, the heart struggles to recoup and maintain energy. One third of patients develop heart…
How somatic mutations shape disease and reveal new drug targets
Scientists reveal how evolution within our own tissues can drive disease, protect cells, and uncover hidden therapeutic targets…
RSV and COVID-19 trigger different immune responses in infants
Young infants hospitalized with respiratory syncytial virus (RSV) often become much sicker compared to those infected with SARS-CoV-2,…
Study sheds light on behavior of yeast cells in the gut
A new study sheds light on the behavior of yeast cells in the gut, paving the way for…
Genome sequencing data reveals new insights into Epstein-Barr virus immunity
The Epstein-Barr virus (EBV) can cause certain types of cancer or autoimmune diseases, but how the body controls…
New spatial omics platform advances biomedical research in Spain
Spatial omics is a new generation of technologies that allow scientists to study cells in their original location…
Key protein in the tuberculosis bacterium helps protect itself from foreign DNA
Researchers at the Indian Institute of Science (IISc), with collaborators from the Institute of Mathematical Sciences (IMSc), have…
New computational method reconstructs how cells decide their fate
Researchers from Kyushu University have developed an innovative computational method, called ddHodge, that can reconstruct the complex dynamics…
Researchers develop powerful tools for microbiome research advancement
The microscopic organisms that fill our bodies, soils, oceans and atmosphere play essential roles in human health and…