New DNA test improves diagnosis of rare genetic disorders
A new test provides a much more complete picture of DNA than current standard diagnostics and leads to…
Favorable lifestyle factors reduce dementia risk across key genetic profiles
With dementia cases expected to nearly triple worldwide by 2050, researchers are increasingly focused on identifying ways to…
MIDAS platform accelerates protein engineering through rapid PCR-based screening
Proteins are critical to life – and to industry. There are countless proteins that could be engineered to…
DNA-guided CRISPR system targets RNA and expands Cas12 beyond gene editing
A DNA-guided CRISPR platform could make RNA detection and control more stable, scalable, and precise, opening new routes…
Research offers clearer genetic blueprint of breast cancer variants
A study led by Dr Jason Pitt, Principal Investigator at the Cancer Science Institute of Singapore (CSI Singapore),…
Dual-pathway protein degradation approach could improve cancer treatment
Targeted protein degradation has become one of the most promising strategies in modern drug discovery, enabling scientists to…
Atomic-level images could improve future COVID-19 antiviral drug design
The closest-ever detailed look at a key enzyme inside the virus that causes COVID-19 could lead to more…
New method predicts cancer patient survival using advanced molecular data
Oregon Health & Science University researchers have developed a first-of-its-kind method to predict cancer patient survival using advanced molecular data from individual…
Base editing corrects genetic mutation responsible for severe form of inherited epilepsy
University of Virginia School of Medicine scientists have used a next-generation form of gene editing to fix the…
New brain circuit discovery offers hope for chronic pain treatment
A new map of a brain circuit specific to chronic pain suggests a promising route to treatment for…
New polygenic risk scores improve prediction of metabolic disease outcomes
Type 2 diabetes (T2D) and obesity are metabolic conditions with many causes, including overlapping and distinct genetic features.…
Transposable elements cause majority of lethal mutations in fruit flies
Most lethal mutations in wild fruit flies are driven by newly transferred jumping genes, not small DNA errors,…