New generation of CRISPR shows safer path to treating genetic diseases
A new generation of CRISPR technology developed at UNSW Sydney offers a safer path to treating genetic diseases…
Gene editing restores hearing and balance in adult mice with DFNA41 deafness
Zheng-Yi Chen, DPhil, associate scientist at the Eaton-Peabody Laboratories, and Ines and Fredrick Yeatts Chair in Otolaryngology, at…
Early use of risdiplam in newborns with SMA shows improvements in motor development
Spinal muscular atrophy (SMA) is a rare genetic condition that causes progressive muscle weakness, which, when untreated, prevents…
Researchers find CFI deficiency alarmingly high in old order Amish
Researchers from the Children’s Hospital of Philadelphia (CHOP) and the Clinic for Special Children found that complement factor…
New research highlights combined impact of genes and lifestyle on dilated cardiomyopathy
An international team, led by scientists from the Victor Chang Cardiac Research Institute has studied around 3000 people…
4,000-year-old sheep tooth sheds light on enigmatic Eurasian plague
Around 5,000 years ago, a mysterious form of plague spread throughout Eurasia, only to disappear 2,000 years later.…
Integrated molecular and detailed anatomical profiling identifies a prognostically adverse subtype of posterior fossa meningiomas: high-risk copy number alterations are associated with midline predilection and predict poor prognosis | Acta Neuropathologica Communications
Patient characteristics The patient characteristics are summarized in a table (Table 1). Among the 132 patients included in this…
Exploring the genetic and clinical landscape of clubfoot
A new publication offers an extensive examination of clubfoot, a congenital deformity known as congenital talipes equinovarus (CTEV),…
Researchers uncover dozens of traits driven by maternal versus paternal genes
By tracing maternal and paternal inheritance without parental DNA, scientists have mapped dozens of parent-specific genetic effects, uncovering…
Scientists link brain lithium loss to early Alzheimer’s changes
A new study reveals that brain lithium depletion occurs early in Alzheimer’s and fuels disease progression, while low-dose…
Genetic testing can guide safer chemotherapy for gastrointestinal cancer patients
For some patients with gastrointestinal (GI) cancers like colorectal and pancreatic cancer, chemotherapy can cause severe, sometimes life-threatening…
Scientists map the genes behind diet and dementia risk
Scientists reveal a new genetic resource from the MIND diet trial, opening the door to precision nutrition strategies…